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Table 3 Proportions (%) of different microbes or microbe groups non-susceptible to some commonly recommended antibiotics and antibiotic regimens

From: Trends in antimicrobial resistance and empiric antibiotic therapy of bloodstream infections at a general hospital in Mid-Norway: a prospective observational study

Microbe/microbe group Antibiotics and antibiotic combinations (2002–2013) P/T alone or in combinations (2006–2013)
PG PGM Imi-penem Cefo-taxime Cefta-zidime Cipro-floxa-cin Total N P/T P/T-G P/T-G-M Total N
Streptococcus pneumoniae§ 0.9 0.9 0.0 0.4 0.4 NRT 226 0.7 0.7 0.7 146
Beta-hemolytic streptococci 0.0 0.0 0.0 0.0 100.0 NRT 104 0.0 0.0 0.0 71
Viridans streptococci 0.0 0.0 0.0 3.5 8.8 NRT 57 0.0 0.0 0.0 42
Staphylococcus aureus# 0.5 0.5 0.0 0.0 100.0 (IR) NRT 218 0.0 0.0 0.0 146
Coagulase-negative staphylococci 13.0 13.0 38.9 38.9 100.0 (IR) NRT 54 41.9 19.4 19.4 31
Enterococcus spp. 9.0 9.0 11.2 100.0 (IR) 100.0 (IR) NRT 89 11.5 9.8 9.8 61
Listeria monocytogenes 0.0 0.0 0.0 100.0 (IR) 100.0 (IR) NRT 8 0.0 0.0 0.0 6
Escherichia coli 1.9 1.9 0.1 1.9 1.9 3.3 686 6.0 0.8 0.8 500
Klebsiella spp. or Proteus spp. 0.0 0.0 5.5 2.2 2.2 4.7 182 7.0 0.0 0.0 143
Other enterobacteria 1.4 1.4 9.5 20.3 21.6 2.9 74 16.9 100.0 100.0 59
Pseudomonas spp. 1.7 1.7 6.9 100.0
(IR)
3.4 8.2 58 5.3 2.6 2.6 38
Other aerobic Gram-negatives 8.9 8.9 8.9 31.1 28.9 6.7 45 23.3 0.0 0.0 30
Anaerobic bacteria 66.1 3.6 0.0 96.4 96.4 NRT 56 5.1 7.7 0.0 39
Mixed bacterial infection 24.8 11.6 13.2 48.8 50.4 NRT 121 11.6 8.1 4.7 86
Candida spp. single or in mixed infection 100.0 (IR) 100.0 (IR) 100.0 (IR) 100.0 (IR) 100.0 (IR) 100.0 (IR) 17 100.0 (IR) 100.0 (IR) 100.0 (IR) 15
Total 6.1 3.5 4.5 17.8 27.8 NRT 1995 7.6 3.0 2.6 1413
  1. §two isolates of penicillin-non-susceptible pneumococci were detected
  2. #one single isolate of methicillin-resistant Staphylococcus aureus (MRSA) and one single isolate of gentamicin-resistant S. aureus were detected
  3. IR, inherently resistant (see Additional file 1: Appendix 1 On inherent (natural) resistance in microbes); NRT, not routinely tested; PG, penicillin-gentamicin; PGM, penicillin-gentamicin-metronidazole; P/T, piperacillin-tazobactam; P/T-G, piperacillin-tazobactam plus gentamicin; P/T-G-M, piperacillin-tazobactam plus gentamicin plus metronidazole
  4. Piperacillin-tazobactam (P/T) was adopted in 2006