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Table 3 Proportions (%) of different microbes or microbe groups non-susceptible to some commonly recommended antibiotics and antibiotic regimens

From: Trends in antimicrobial resistance and empiric antibiotic therapy of bloodstream infections at a general hospital in Mid-Norway: a prospective observational study

Microbe/microbe group

Antibiotics and antibiotic combinations (2002–2013)

P/T alone or in combinations (2006–2013)

PG

PGM

Imi-penem

Cefo-taxime

Cefta-zidime

Cipro-floxa-cin

Total N

P/T

P/T-G

P/T-G-M

Total N

Streptococcus pneumoniae§

0.9

0.9

0.0

0.4

0.4

NRT

226

0.7

0.7

0.7

146

Beta-hemolytic streptococci

0.0

0.0

0.0

0.0

100.0

NRT

104

0.0

0.0

0.0

71

Viridans streptococci

0.0

0.0

0.0

3.5

8.8

NRT

57

0.0

0.0

0.0

42

Staphylococcus aureus#

0.5

0.5

0.0

0.0

100.0 (IR)

NRT

218

0.0

0.0

0.0

146

Coagulase-negative staphylococci

13.0

13.0

38.9

38.9

100.0 (IR)

NRT

54

41.9

19.4

19.4

31

Enterococcus spp.

9.0

9.0

11.2

100.0 (IR)

100.0 (IR)

NRT

89

11.5

9.8

9.8

61

Listeria monocytogenes

0.0

0.0

0.0

100.0 (IR)

100.0 (IR)

NRT

8

0.0

0.0

0.0

6

Escherichia coli

1.9

1.9

0.1

1.9

1.9

3.3

686

6.0

0.8

0.8

500

Klebsiella spp. or Proteus spp.

0.0

0.0

5.5

2.2

2.2

4.7

182

7.0

0.0

0.0

143

Other enterobacteria

1.4

1.4

9.5

20.3

21.6

2.9

74

16.9

100.0

100.0

59

Pseudomonas spp.

1.7

1.7

6.9

100.0

(IR)

3.4

8.2

58

5.3

2.6

2.6

38

Other aerobic Gram-negatives

8.9

8.9

8.9

31.1

28.9

6.7

45

23.3

0.0

0.0

30

Anaerobic bacteria

66.1

3.6

0.0

96.4

96.4

NRT

56

5.1

7.7

0.0

39

Mixed bacterial infection

24.8

11.6

13.2

48.8

50.4

NRT

121

11.6

8.1

4.7

86

Candida spp. single or in mixed infection

100.0 (IR)

100.0 (IR)

100.0 (IR)

100.0 (IR)

100.0 (IR)

100.0 (IR)

17

100.0 (IR)

100.0 (IR)

100.0 (IR)

15

Total

6.1

3.5

4.5

17.8

27.8

NRT

1995

7.6

3.0

2.6

1413

  1. §two isolates of penicillin-non-susceptible pneumococci were detected
  2. #one single isolate of methicillin-resistant Staphylococcus aureus (MRSA) and one single isolate of gentamicin-resistant S. aureus were detected
  3. IR, inherently resistant (see Additional file 1: Appendix 1 On inherent (natural) resistance in microbes); NRT, not routinely tested; PG, penicillin-gentamicin; PGM, penicillin-gentamicin-metronidazole; P/T, piperacillin-tazobactam; P/T-G, piperacillin-tazobactam plus gentamicin; P/T-G-M, piperacillin-tazobactam plus gentamicin plus metronidazole
  4. Piperacillin-tazobactam (P/T) was adopted in 2006