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Table 5 Variables included in univariate logistic regression and significant associated (P < 0.01) with hospital mortality in 268 ICI patients receiving antifungal therapy in the China-SCAN study based only on patients who died in hospital or completed treatment and were discharged at their physician’s discretion

From: Initial therapeutic strategy of invasive candidiasis for intensive care unit patients: a retrospective analysis from the China-SCAN study

Variables Survivors
N = 139
Non-survivors
N = 99
P-value
Age, years 58.6 ± 20.6 66.0 ± 19.8 0.006
APACHE II score on ICU admission 19.0 ± 8.9 22.5 ± 8.4 0.002
SOFA score on ICU admission 6.6 ± 3.5 7.9 ± 3.8 0.008
APACHE II score at diagnosis 18.8 ± 8.5 22.7 ± 7.0 0.000
SOFA score at diagnosis 6.4 ± 3.6 7.8 ± 3.8 0.003
Initial antifungal therapy strategies
(empirical : pre-emptive : targeted)
66 : 37 : 36 35 : 35 : 29 0.004
  1. APACHE II Acute Physiology and Chronic Health Evaluation II, SOFA sequential organ failure assessment
  2. Continuous variables are expressed as the means ± SD or medians (IQR). All the other data are raw numbers (%)