Skip to main content

Table 3 Multivariate analysis of cocaine/crack use and liver fibrosis progression

From: Cocaine/crack use is not associated with fibrosis progression measured by AST-to-Platelet Ratio Index in HIV-HCV co-infected patients: a cohort study

  Recent cocaine/crack use
  HR 95% CI
Time independent variables (at baseline)
 Cocaine/crack use ever at baseline 0.96 0.58, 1.57
 Baseline age (per 10 years) 1.04 0.86, 1.27
 Female sex 1.45 1.04, 2.01
 Baseline HCV infection duration (per 5 years) 1.00 0.92, 1.10
 Baseline ln (APRI) 2.84 1.94, 4.16
Time updated variables
 Recent cocaine/crack use 0.88 0.63, 1.25
 Recent other drug usea 1.07 0.77, 1.49
 Current alcohol abuseb 1.63 1.09, 2.42
 CD4 count (per 100 cells/μL) 0.90 0.84, 0.96
  1. aHeroin and opiates, steroids, methylphenidate, hallucinogens (PCP, LSD), benzodiazepine, barbiturates, methamphetamine, amphetamine, other
  2. bDefined as >6 drinks at least once a month and >2 drinks on a typical day when drinking