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Table 1 Efficacy and Kappa values of diagnostic yield of different diagnostic methods used in the diagnosis of TBLN

From: Concentration of fine needle aspirates similar to molecular method improves sensitivity of the diagnosis of tuberculous lymphadenitis in Addis Ababa, Ethiopia

Diagnostics Methods

Culture

Sensitivity (%)

Specificity (%)

Kappa (95% CI)

 

Positive n (%)

Negative n (%)

Direct ZN staining

Positive (n = 39)

32 (82.1)

7 (17.9)

43.2

87.9

0.32 (0.21–0.41)

Negative (n = 93)

42 (45.2)

51 (54.8)

   

Concentrated ZN staining

Positive (n = 86)

70 (81.4)

16 (18.6)

94.5

72.4

0.62 (0.57–0.81)

Negative (n = 46)

4 (8.7)

42 (89.3)

   

Direct PCR

Positive (n = 91)

69 (75.8)

22 (24.2)

93.2

62.1

0.58 (0.41–0.71)

Negative (n = 41)

5 (12.2)

36 (87.8)

   

Cytology

Positive (n = 110)

71 (64.5)

39 (35.5)

95.4

32.8

0.26 (0.22–0.046)

Negative (n = 22)

3 (13.6)

19 (86.4)