Skip to main content

Table 3 Risk factors for mortality of patients in univariate/multivariate Cox’s proportional hazard models

From: Hyponatremia is a marker of disease severity in HIV-infected patients: a retrospective cohort study

  Univariate Model Multivariate Model
Risk factors Hazard ratio (95% Confidence interval) P-value Hazard ratio (95% Confidence interval) P-value
Age < 35 years 0.51 (0.29-0.87) 0.014 0.91 (0.48-1.73) 0.782
Female gender 1.68 (1.01-2.80) 0.045 1.65 (0.86-3.16) 0.132
African ethnicity 1.29 (0.77-2.15) 0.366   
Homo-bisexuel orientation 0.28 (0.13-0.59) 0.0003 0.90 (0.34-2.34) 0.827
Natremia < 135 mmol/l 3.94 (2.30-6.74) <0.0001 1.03 (0.54-1.97) 0.935
AIDS 8.83 (5.18-15.06) <0.0001 5.24 (2.59-10.62) <0.0001
CD4 cell count < 350/μl 11.71 (4.66-29.43) <0.0001 6.58 (1.89-23.06) 0.003
HIV viral load > 100 000 copies/ml 3.36 (1.87-6.03) <0.0001 1.15 (0.56-2.37) 0.702
Hepatitis B 0.23 (0.032-1.71) 0.172   
Hepatitis C 2.54 (1.15-5.60) 0.0259 2.70 (1.172-6.23) 0.02
Fib4 score > 3.25 3.84 (1.95-7.55) <0.0001 1.69 (0.77-3.74) 0.192
Anemia 4.30 (2.95-6.27) <0.0001 1.15 (0.75-2.84) 0.263
Hyperlipidemia 0.93 (0.54-1.59) 0.892   
Diabetes mellitus 4.22 (1.96-9.11) 0.0011 2.07 (0.88-4.85) 0.096
Inclusion period 1998-2004 2.54 (1.52-4.25) 0.0004 1.32 (0.72 – 2.42) 0.372