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Fig. 8 | BMC Infectious Diseases

Fig. 8

From: Early rising asexual parasitaemia in Nigerian children following a first dose of artemisinin-based combination treatments of falciparum malaria

Fig. 8

Parasite DNA clone number, area under curve of number of DNA clones versus time, and elimination kinetics of parasite DNA clones in age-, pre-treatment parasitaemia- and same treatment-matched malarious children with (1) and without (2) ERAP treated with artesunate-amodiaquine. Panel a shows increase in parasite DNA clones from one to five 1 h post-initiation of treatment. Parasite DNA clearance time was 48 h. Panel b shows stable number of DNA clone (one at all times) pre- and post-initiation of treatment and no change in parasite DNA clone number following treatment. Parasite DNA clearance time was 24 h. Panels c and d show area under curve of number of clones versus time in children with and without ERAP, respectively. Panel e and f show monoexponential terminal elimination of DNA clones in children with and without ERAP, respectively. Note: Declines in DNA clone numbers were monoexponential

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BMC Infectious Diseases

ISSN: 1471-2334

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