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Table 1 Frequency of positive cultures and percentages of uropathogens in 176 children with spina bifida on clean intermittent catheterization on and off antibiotic prophylaxis

From: The influence of antibiotic prophylaxis on bacterial resistance in urinary tract infections in children with spina bifida

  Total Stop group Continuing group  
Number % Number % Number % p-value for stop versus continue
Patients with only negative urine tests 23 13.1 11 12.5 12 13.6  
Patients with one or more positive cultures 153 86.9 77 87.5 76 86.4 Pearson chi-square 0.635
SBU 137 77.8 70 79.5 67 76.1 1,000
UTI 107 60.8 55 62.5 52 59.1 0.643
Number of positive cultures 713 14.5 370   343   
SBU 398 55.8 199 53.8 199 58.0  
UTI 315 44.2 171 46.2 144 42.0  
   CI   CI   CI  
Mean number of positive cultures per patient (95% CI) 4.66 (4.1-5.2) 4.81 (4.1-5.5) 4.51 (3.8-5.2) negative binominal analysis 0.573
SBU 2.60 (2.3-2.9) 2.58 (2.2-3.0) 2.62 (2.1-3.1) 0.915
UTI 2.06 (1.7-2.4) 2.22 (1.7-2.7) 1.89 (1.4-2.4) 0.364
Uropathogens in positive cultures (% of positive cultures)   %   %   %  
E.coli 387 54.3 200 54.1 187 54.5 Pearson chi-square 0.429
Non E.coli 326 45.7 170 45.9 156 45.5  
Gram negative 631 88.5 326 88.1 305 88.9 0.901
Enterobacteriaceae        
AmpC negative        
E.coli 387 54.3 200 54.1 187 54.5  
Klebsiella pneumoniae 42 5.9 21 5.7 21 6.1  
Proteus mirabilis 34 4.8 15 4.1 19 5.5  
Klebsiella oxytoca 21 2.9 16 4.3 5 1.5  
AmpC positive        
Enterobacter cloacae 18 2.5 10 2.7 8 2.3  
Citrobacter freundii 17 2.4 11 3.0 6 1.7  
Non fermenting bacilli        
Pseudomonas auroginosa 47 6.6 29 7.8 18 5.2  
Other 65 9.1 24 6.5 41 12.0  
Gram positive 82 11.5 44 11.9 38 11.1 0.762
Enterococcal species 56 7.9 30 8.1 26 7.6  
Staphylococcus aureus 18 2.5 10 2.7 8 2.3  
Other gram positive 8 1.1 4 1.1 4 1.2  
CI = 95% confidence interval        
SBU = significant bacteriuria        
UTI = urinary tract infection