Skip to main content

Table 2 Baseline tropism predicted by the geno2pheno clinical and clonal models, respectively, at the fpr10% level

From: Monophylogenetic HIV-1C epidemic in Ethiopia is dominated by CCR5-tropic viruses–an analysis of a prospective country-wide cohort

  Clinical model FPR 10% Clonal model FPR 10% Concordance between clinical and clonal modelsa
R5 X4 R5/X4 p-value* R5 X4 R5/X4 p-value* R5-R5 R5-X4 X4-R5 X4-X4 p-value**
Number (%) 285 (81) 60 (17) 7 (2)   291 (82.7) 50 (14.2) 11 (3.1)   245 (69.6) 40 (11.4) 46 (13.0) 21 (6.0)  
CD4 cells/ul median (IQR) 132 (76–193) 41 (21–98) 130 (107–220) <0.001 125 (67–189) 89 (42–140) 160 (72–177) 0.08 135 (77–196) 127 (74–188) 55 (21–128) 70 (22–91) <0.001
VL median (IQR) 5.3 (4.8–5.8) 5.4 (5.1–5.8) 5.3 (4.4–5.7) 0.18 5.4 (4.9–5.8) 5.4 (5–5.9) 5.4 (4.7–5.7 0.50 5.3 (4.8–5.8) 5.4 (5.1–5.9) 5.3 (4.4–5.7) 5.8 (5.3–5.9) 0.170
  1. *Mann-Whitney U-Test; **Kruskal Wallis Test; aR5-R5: both models predicted R5 virus; R5-X4: clinical model predicted R5 virus and clonal model predicted X4 virus; X4-R5: clinical model predicted X4 virus and clonal model predicted R5 virus; X4-X4: both models predicted X4 virus. VL: viral load (copies/ml)