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Table 2 Maternal characteristics among symptomatic neonates, following primary versus non-primary maternal infection

From: Symptomatic congenital cytomegalovirus disease following non-primary maternal infection: a retrospective cohort study

 

Primary (n = 95)

Non-primary (n = 12)

P value

Maternal age, years

29.12 ± 5.12

27.77 ± 4.60

0.452

Maternal chronic disease

14 (15.1%)

3 (27.3%)

0.382

High professional risk

19 (20%)

2 (16.7%)

0.999

Obstetrical history

 Parity

2.24 ± 1.21

2.16 ± 1.69

0.848

 Live births

2.03 ± 0.93

2.0 ± 1.41

0.918

 Abortions

0.21 ± 0.74

0.17 ± 0.39

0.847

 Parity, with living children (≥1)

75 (78.9%)

7 (58.3%)

0.146

Complications during pregnancy

9 (9.9%)

4 (33.3%)

0.038

Medication use during pregnancy

16 (16.8%)

6 (50%)

0.016

Febrile disease at CMV diagnosis

31 (38.8%)

1 (8.3%)

0.103

Gestational age at CMV diagnosis:

19.50 ± 8.38

19.16 ± 13.51

0.928

 1st trimester

44 (46.3%)

3 (25%)

0.318

 2nd trimester

42 (44.2%)

1 (8.3%)

0.03

 3rd trimester

9 (9.5%)

2 (16.7%)

0.356

Maternal serology at CMV diagnosis

 Positive IgG

81 (85.3%)

12 (100%)

<.0001

 IgG Seroconversion

79 (83.1%)

--

--

 Positive IgM

72 (75.8%)

3 (25%)

0.0008

 Low avidity IgG

33 (34.7%)

--

--

  1. Data presented as n(%) or mean ± 1 Standard Deviation
  2. CMV Cytomegalovirus