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Table 2 Maternal characteristics among symptomatic neonates, following primary versus non-primary maternal infection

From: Symptomatic congenital cytomegalovirus disease following non-primary maternal infection: a retrospective cohort study

  Primary (n = 95) Non-primary (n = 12) P value
Maternal age, years 29.12 ± 5.12 27.77 ± 4.60 0.452
Maternal chronic disease 14 (15.1%) 3 (27.3%) 0.382
High professional risk 19 (20%) 2 (16.7%) 0.999
Obstetrical history
 Parity 2.24 ± 1.21 2.16 ± 1.69 0.848
 Live births 2.03 ± 0.93 2.0 ± 1.41 0.918
 Abortions 0.21 ± 0.74 0.17 ± 0.39 0.847
 Parity, with living children (≥1) 75 (78.9%) 7 (58.3%) 0.146
Complications during pregnancy 9 (9.9%) 4 (33.3%) 0.038
Medication use during pregnancy 16 (16.8%) 6 (50%) 0.016
Febrile disease at CMV diagnosis 31 (38.8%) 1 (8.3%) 0.103
Gestational age at CMV diagnosis: 19.50 ± 8.38 19.16 ± 13.51 0.928
 1st trimester 44 (46.3%) 3 (25%) 0.318
 2nd trimester 42 (44.2%) 1 (8.3%) 0.03
 3rd trimester 9 (9.5%) 2 (16.7%) 0.356
Maternal serology at CMV diagnosis
 Positive IgG 81 (85.3%) 12 (100%) <.0001
 IgG Seroconversion 79 (83.1%) -- --
 Positive IgM 72 (75.8%) 3 (25%) 0.0008
 Low avidity IgG 33 (34.7%) -- --
  1. Data presented as n(%) or mean ± 1 Standard Deviation
  2. CMV Cytomegalovirus