Skip to main content

Table 2 Univariate and multivariate analysis for blood stream infection

From: Risk factors and characteristics of blood stream infections in patients with newly diagnosed multiple myeloma

 

Univariate

Multivariate

Odds ratio

95% CI

P value*

Odds ratio

95% CI

P value*

Gender (female vs. male)

1.36

0.571–3.266

0.49

-

-

-

Age (≥ 65 vs. < 65)

1.48

0.591–3.681

0.40

-

-

-

Myeloma subgroup

 IgG vs. Non-IgG

1.06

0.469–2.410

0.88

-

-

-

 IgA vs. Non-IgA

1.12

0.472–2.646

0.80

   

Immunoglobulin status

1.18

0.324–4.303

0.80

-

-

-

 Severe Ig deficiencya vs. Others

      

ISS stage

 III vs. I/II

3.54

1.365–9.203

<0.01*

2.69

1.003–7.190

0.049

ECOG PS

 Score > 2 vs. 0–2

4.39

1.849–10.403

<0.01*

3.58

1.478–8.690

0.005

Hb (< 10 g/dL vs. ≥ 10 g/dL)

3.422

1.240–9.444

0.02*

-

-

-

Ca (> 12 mg/dL vs. < 12 mg/dL)

3.095

1.013–9.454

0.04*

-

-

-

Cr (≥ 2.0 mg/dL vs. < 2.0 mg/dL)

3.091

1.341–7.126

0.01*

-

-

-

ALC (< 1000/cumm vs. ≥ 1000/cumm)

1.251

0.527–2.968

0.61

   
  1. Abbreviations: IgG Immunoglobulin G, IgA Immunoglobulin A, Ig Immunoglobulin, ISS International Staging System, ECOG PS Eastern Cooperative Oncology Group Performance Status, Hb Hemoglobin, Ca Calcium; Cr Creatinine, ALC Absolute lymphocyte count
  2. aSevere Ig deficiency: both of the non-myeloma immunoglobulin levels less than one-fourth of lower normal limit
  3. *Significant p < 0.05 in univariate models were entered in the Cox regression multivariate model using conditional backward analysis