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Table 2 Univariate and multivariate analysis for blood stream infection

From: Risk factors and characteristics of blood stream infections in patients with newly diagnosed multiple myeloma

  Univariate Multivariate
Odds ratio 95% CI P value* Odds ratio 95% CI P value*
Gender (female vs. male) 1.36 0.571–3.266 0.49 - - -
Age (≥ 65 vs. < 65) 1.48 0.591–3.681 0.40 - - -
Myeloma subgroup
 IgG vs. Non-IgG 1.06 0.469–2.410 0.88 - - -
 IgA vs. Non-IgA 1.12 0.472–2.646 0.80    
Immunoglobulin status 1.18 0.324–4.303 0.80 - - -
 Severe Ig deficiencya vs. Others       
ISS stage
 III vs. I/II 3.54 1.365–9.203 <0.01* 2.69 1.003–7.190 0.049
ECOG PS
 Score > 2 vs. 0–2 4.39 1.849–10.403 <0.01* 3.58 1.478–8.690 0.005
Hb (< 10 g/dL vs. ≥ 10 g/dL) 3.422 1.240–9.444 0.02* - - -
Ca (> 12 mg/dL vs. < 12 mg/dL) 3.095 1.013–9.454 0.04* - - -
Cr (≥ 2.0 mg/dL vs. < 2.0 mg/dL) 3.091 1.341–7.126 0.01* - - -
ALC (< 1000/cumm vs. ≥ 1000/cumm) 1.251 0.527–2.968 0.61    
  1. Abbreviations: IgG Immunoglobulin G, IgA Immunoglobulin A, Ig Immunoglobulin, ISS International Staging System, ECOG PS Eastern Cooperative Oncology Group Performance Status, Hb Hemoglobin, Ca Calcium; Cr Creatinine, ALC Absolute lymphocyte count
  2. aSevere Ig deficiency: both of the non-myeloma immunoglobulin levels less than one-fourth of lower normal limit
  3. *Significant p < 0.05 in univariate models were entered in the Cox regression multivariate model using conditional backward analysis