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Table 5 Mean cyst burden per mouse brain 4 weeks after challenge with 20 cysts of Toxoplasma gondii PRU strain per mouse

From: Vaccination with toxofilin DNA in combination with an alum-monophosphoryl lipid A mixed adjuvant induces significant protective immunity against Toxoplasma gondii

Challenged groupa Brain cysts per mouse (mean ± SD)b
PBS 3042.43 ± 115.17
alum 2834.45 ± 100.89
MPLA 2767.36 ± 103.45
alum-MPLA 2532.56 ± 99.45
pEGFP-toxofilin 2048.79 ± 87.44*
alum-toxofilin 1764.17 ± 78.45*
MPLA-toxofilin 1563.42 ± 80.48*
alum-MPLA-toxofiln 1034.49 ± 45.87*#
  1. a10 mice from each group were challenged intragastrically by 20 cysts 2 weeks after the last immunization. All samples were run for three times
  2. bThe mean number of cysts of each group was obtained from every mice brain cysts in the group
  3. *Compared with PBS, alum, MPLA, alum-MPLA, P < 0.05
  4. #Compared with pEGFP- toxofilin, alum-toxofilin and MPLA-toxofilin, P < 0.05