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Table 4 Percentages of T lymphocyte subsets in immunized micea by flow cytometry

From: Vaccination with toxofilin DNA in combination with an alum-monophosphoryl lipid A mixed adjuvant induces significant protective immunity against Toxoplasma gondii

Groups

CD3+ CD4+ CD8− (%)

CD3+ CD8+ CD4− (%)

PBS

15.31 ± 0.12

7.35 ± 0.18

alum

17.34 ± 0.34

9.62 ± 0.29

MPLA

17.92 ± 0.25

9.08 ± 0.24

alum-MPLA

18.49 ± 0.19

10.13 ± 0.30

pEGFP- toxofilin

20.17 ± 0.53*

12.48 ± 0.43*

alum-toxofilin

21.37 ± 0.76*

12.98 ± 0.45*

MPLA-toxofilin

27.46 ± 0.97*#

17.39 ± 0.98*#

alum-MPLA-toxofiln

32.38 ± 1.19*#

20.68 ± 1.37*#

  1. aSplenocytes from 3 mice per group at the fourth week after the final immunization
  2. *Compared with PBS, alum, MPLA, alum-MPLA. P <0.05
  3. #Compared with alum-toxofilin or pEGFP-toxofilin groups, P <0.05
  4. Results are presented as means ± SD of three replicate determinations