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Table 4 Percentages of T lymphocyte subsets in immunized micea by flow cytometry

From: Vaccination with toxofilin DNA in combination with an alum-monophosphoryl lipid A mixed adjuvant induces significant protective immunity against Toxoplasma gondii

Groups CD3+ CD4+ CD8− (%) CD3+ CD8+ CD4− (%)
PBS 15.31 ± 0.12 7.35 ± 0.18
alum 17.34 ± 0.34 9.62 ± 0.29
MPLA 17.92 ± 0.25 9.08 ± 0.24
alum-MPLA 18.49 ± 0.19 10.13 ± 0.30
pEGFP- toxofilin 20.17 ± 0.53* 12.48 ± 0.43*
alum-toxofilin 21.37 ± 0.76* 12.98 ± 0.45*
MPLA-toxofilin 27.46 ± 0.97*# 17.39 ± 0.98*#
alum-MPLA-toxofiln 32.38 ± 1.19*# 20.68 ± 1.37*#
  1. aSplenocytes from 3 mice per group at the fourth week after the final immunization
  2. *Compared with PBS, alum, MPLA, alum-MPLA. P <0.05
  3. #Compared with alum-toxofilin or pEGFP-toxofilin groups, P <0.05
  4. Results are presented as means ± SD of three replicate determinations