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Table 2 Ligation strength analysis of Tg-toxofilin for MHC class II molecules using SYFPEITHIa

From: Vaccination with toxofilin DNA in combination with an alum-monophosphoryl lipid A mixed adjuvant induces significant protective immunity against Toxoplasma gondii

MHC II Alleleb Start-Stopc Sequence Percent: e Rankd
HLA-DRB1*01:01 91-105 LQTVHQLGAVALTPE 0.39
HLA-DRB1*01:01 9-23 LAAFLLLIVGSLLT 0.42
H2-IAb 78-92 EERLIAGQAKAAALQ 3.04
H2-IAb 96-110 QLGAVALTPEQAKAA 6.58
H2-IAd 178-192 HYHVTKQAALAGQIL 0.13
H2-IAd 231-245 QHASQLKKVGAMPSS 0.62
H2-IEd 169-183 KARKLFQRRHYHVTK 13.80
H2-IEd 28-42 VQLSEGMKRLSMRGR 21.98
  1. aThe prediction was run for three times
  2. bH2-IAb, H2-IAd and H2-IEd alleles are mouse MHC class II molecules; the HLADRB1*01:01 allele is a human MHC class II molecule
  3. cWe chose 15 amino acids for analysis each time
  4. dLow percentile = high level binding, high percentile = low level binding