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Table 3 Comparison of LAMP and smear in series and parallel for the diagnosis of pulmonary tuberculosis

From: Comparison of loop-mediated isothermal amplification assay and smear microscopy with culture for the diagnostic accuracy of tuberculosis

  

Culture+

Culture–

Se % (95% CI)

Sp % (95% CI)

PPV (%)

NPV (%)

κ

2tests in serial

Pos

19

0

67.8(49.3–82.1)

100(92.3–100)

100

84.7

0.83

Neg

9

50

     

2tests in parallel

Pos

24

2

85.7(68.5–94.3)

96(86.5–98.9)

92.3

92.3

0.786

Neg

4

48

     
  1. Se Sensitivity, Sp Specificity, PPV Positive predictive value. NPV Negative predictive value, κ Kappa value, CI confidence interval