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Table 2 Laboratory data and radiographic findings in HIV negative patients with cryptococcal meningitis (CM) and tuberculous meningitis (TBM)

From: Comparison of clinical features and prognostic factors in HIV-negative adults with cryptococcal meningitis and tuberculous meningitis: a retrospective study

Variables CM (N=126) TBM (N=105) P-value
CSF
 WBC (cells/mm3), Median (IQR) 80.00 (20.00–200.00) 120.00 (59.00–295.00) 0.005
 Total protein (mg/dL), Median (IQR) 0.83 (0.58–1.32) 1.53(0.99–2.66) <0.001
 Glucose (mmol/L), Median (IQR) 1.57 (0.80–2.56) 1.78(1.10–2.35) 0.694
 Chloride (mmol/L), (mean±SD) 118.11±6.67 111.40±7.59 0.169
 Open pressure > 220mm H2O 98 (77.78%) 75 (71.4%) 0.289
Serum
 Albumin(g/L), (mean±SD) 37.77±5.29 36.61±5.20 0.688
 WBC (×109/L), (mean±SD) 8.89±3.51 7.46±3.45 0.701
 Neutrophile (%) 78.44±10.85 75.92±11.33 0.690
 Hemoglobin (g/L), (mean±SD) 122.83±23.05 118.50±22.71 0.548
 CD3+ T lymphocyte (%) 65.11±14.25 70.96±13.20 0.533
 CD4+ T lymphocyte (%) 28.71±10.46 34.77±11.27 0.542
 CD8+ T lymphocyte (%) 25.40±8.57 25.19±10.26 0.139
 CD4/CD8 ratio 1.22±0.59 1.71±1.12 0.003
Brain images (CT/MRI)
 Cerebral ischemia/infarction 55 (43.7%) 30 (28.6%) 0.028
 Demyelination 30 (23.8%) 14 (9.5%) 0.046
 Meningeal enhancement 23 (18.3%) 20 (16.0%) 0.877
 Hydrocephalus 16 (12.7%) 17(16.2%) 0.709
 Encephalitis 14 (11.1%) 40 (38.1%) <0.001
 Cerebral edema 4 (3.17%) 13 (12.4%) 0.010
 Others 4 (3.17%) 8 (7.6%) 0.147
 Normal 20 (15.9%) 12 (11.4%) 0.347
  1. CSF cerebrospinal fluid, WBC white blood count, MRI magnetic resonance imaging