Table 2 Laboratory data and radiographic findings in HIV negative patients with cryptococcal meningitis (CM) and tuberculous meningitis (TBM)

 WBC (cells/mm³), Median (IQR)

80.00 (20.00–200.00)

120.00 (59.00–295.00)

0.005

 Total protein (mg/dL), Median (IQR)

0.83 (0.58–1.32)

1.53(0.99–2.66)

<0.001

 Glucose (mmol/L), Median (IQR)

1.57 (0.80–2.56)

1.78(1.10–2.35)

0.694

 Chloride (mmol/L), (mean±SD)

118.11±6.67

111.40±7.59

0.169

 Open pressure > 220mm H₂O

98 (77.78%)

75 (71.4%)

0.289

 Albumin(g/L), (mean±SD)

37.77±5.29

36.61±5.20

0.688

 WBC (×10⁹/L), (mean±SD)

8.89±3.51

7.46±3.45

0.701

 Neutrophile (%)

78.44±10.85

75.92±11.33

0.690

 Hemoglobin (g/L), (mean±SD)

122.83±23.05

118.50±22.71

0.548

 CD3⁺ T lymphocyte (%)

65.11±14.25

70.96±13.20

0.533

 CD4⁺ T lymphocyte (%)

28.71±10.46

34.77±11.27

0.542

 CD8⁺ T lymphocyte (%)

25.40±8.57

25.19±10.26

0.139

 CD4/CD8 ratio

1.22±0.59

1.71±1.12

0.003

 Cerebral ischemia/infarction

55 (43.7%)

30 (28.6%)

0.028

 Demyelination

30 (23.8%)

14 (9.5%)

0.046

 Meningeal enhancement

23 (18.3%)

20 (16.0%)

0.877

 Hydrocephalus

16 (12.7%)

17(16.2%)

0.709

 Encephalitis

14 (11.1%)

40 (38.1%)

<0.001

 Cerebral edema

4 (3.17%)

13 (12.4%)

0.010

 Others

4 (3.17%)

8 (7.6%)

0.147

 Normal

20 (15.9%)

12 (11.4%)

0.347