TY - JOUR AU - Lau, Andrew AU - Kong, Fabian AU - Fairley, Christopher K. AU - Donovan, Basil AU - Chen, Marcus AU - Bradshaw, Catriona AU - Boyd, Mark AU - Amin, Janaki AU - Timms, Peter AU - Tabrizi, Sepehr AU - Regan, David G. AU - Lewis, David A. AU - McNulty, Anna AU - Hocking, Jane S. PY - 2017 DA - 2017/01/06 TI - Treatment efficacy of azithromycin 1 g single dose versus doxycycline 100 mg twice daily for 7 days for the treatment of rectal chlamydia among men who have sex with men – a double-blind randomised controlled trial protocol JO - BMC Infectious Diseases SP - 35 VL - 17 IS - 1 AB - Rectal infection with Chlamydia trachomatis is one of the most common bacterial sexually transmissible infections among men who have sex with men (MSM) with diagnosis rates continuing to rise. Current treatment guidelines recommend either azithromycin 1 g single dose or doxycycline 100 mg twice daily for 7 days. However, there are increasing concerns about treatment failure with azithromycin. We are conducting the first randomised controlled trial (RCT) to compare treatment efficacy of azithromycin versus doxycycline for the treatment of rectal chlamydia in MSM. SN - 1471-2334 UR - https://doi.org/10.1186/s12879-016-2125-7 DO - 10.1186/s12879-016-2125-7 ID - Lau2017 ER -