| HBV DNA Low | HBV DNA High | P |
---|---|---|---|
Subject number | 131 | 196 | Â |
Age | 45.66 ± 11.62 | 43.24 ± 10.83 | 0.059 |
Gender | |||
  Male | 115 (87.79%) | 165 (84.18%) | 0.363 |
  Female | 16 (12.21%) | 31 (15.82%) |  |
Liver Histology | |||
 ISHAK Fibrosis Stages | |||
  0 | 2 (0.61%) | 0 (0%) | 0.164 |
  1 | 15 (11.45%) | 25 (12.76%) |  |
  2 | 16 (12.21%) | 35 (17.86%) |  |
  3 | 53 (40.46%) | 57 (29.08%) |  |
  4 | 11 (8.40%) | 22 (11.22%) |  |
  5 | 29 (22.14%) | 45 (22.96%) |  |
  6 | 5 (3.82%) | 12 (6.12%) |  |
 Piecemeal necrosis | |||
  0 | 45 (34.35%) | 56 (28.57%) | 0.234 |
  1 | 68 (51.91%) | 97 (49.49%) |  |
  2 | 15 (11.45%) | 32 (16.33%) |  |
  3 | 3 (2.29%) | 11 (5.61%) |  |
 Confluent necrosis | |||
  0 | 126 (96.18%) | 181 (92.35%) | 0.368 |
  1 | 1 (0.76%) | 5 (2.55%) |  |
  2 | 0 (0%) | 2 (1.02%) |  |
  3 | 1 (0.76%) | 0 (0%) |  |
  4 | 3 (2.29%) | 7 (3.57%) |  |
  5 | 0 (0%) | 1 (0.51%) |  |
 Focal (spotty) lytic necrosis, /apoptosis and focal inflammation | |||
  0 | 0 (0%) | 2 (1.02%) | 0.001 |
  1 | 53 (40.46%) | 40 (20.41%) |  |
  2 | 54 (41.22%) | 107 (54.59%) |  |
  3 | 21 (16.03%) | 46 (23.47%) |  |
  4 | 3 (2.29%) | 1 (0.51%) |  |
 Portal inflammation | |||
  0 | 4 (3.05%) | 2 (1.02%) | 0.142 |
  1 | 38 (29.01%) | 39 (19.90%) |  |
  2 | 36 (27.48%) | 67 (34.18%) |  |
  3 | 49 (37.40%) | 74 (37.76%) |  |
  4 | 4 (3.05%) | 13 (6.63%) |  |
  5 | 0 (0%) | 1 (0.51%) |  |
 Viral serology | |||
  HBV DNA (log10 IU/ml) | 4.67 ± 1.22 | 7.48 ± 0.82 | <0.001 |
  HBeAg positive | 36 (27.48%) | 110 (56.12%) | <0.001 |
  HBsAg (log10 IU/ml) | 2.83 ± 0.97 | 3.67 ± 0.83 | <0.001 |
 Serum biochemistry | |||
  ALT (IU/L) | 161.20 ± 179.34 | 188.07 ± 168.45 | 0.175 |
  AST (IU/L) | 86.41 ± 89.06 | 120.77 ± 138.86 | 0.007 |
  Bilirubin (mg/dL) | 1.00 ± 0.50 | 0.97 ± 0.36 | 0.559 |
  Albumin (g/dL) | 4.58 ± 0.28 | 4.54 ± 0.39 | 0.418 |
  Gamma-glutamyltransferase (IU/L) | 56.79 ± 42.31 | 61.58 ± 49.84 | 0.505 |
  Platelet (1000/mm3) | 189.09 ± 49.34 | 190.23 ± 50.96 | 0.84 |
  Hemoglobin (g/dL) | 15.32 ± 1.34 | 15.12 ± 1.37 | 0.26 |