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Table 1 IC50 values for SAG1 and ROM4 peptide binding to MHC class II molecules obtained using the immune epitope databasea

From: Protection via a ROM4 DNA vaccine and peptide against Toxoplasma gondii in BALB/c mice

MHC II Alleleb

Start-Stopc

Percentile Rankd

SAG1

ROM4

SAG1

ROM4

HLA-DRB1*01:01

12–26

570–584

0.88

0.09

35–49

399–413

2.74

0.6

H2-IAb

26–40

483–497

2.15

1.75

297–313

42–56

2.81

1.95

H2-IAd

21–35

502–516

0.34

0.39

168–182

529–543

1.22

0.58

H2-IEd

14–28

179–193

18.45

4.91

34–48

412–426

30.62

11.21

  1. a The immune epitope database (http://tools.immuneepitope.org/mhcii). The prediction was run for three times
  2. b H2-IAb, H2-IAd and H2-IEd alleles are mouse MHC class II molecules; the HLA-DRB1*01:01 allele is a human MHC class II molecule
  3. c We chose 15 amino acids for analysis each time
  4. d Low percentile = high level binding, high percentile = low level binding
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BMC Infectious Diseases

ISSN: 1471-2334

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