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Table 2 HBsAg prevalence of acute and chronic liver disease patients in different regions of Ethiopia from 1984 to 2013

From: Hepatitis viruses in Ethiopia: a systematic review and meta-analysis

Sampling year

Study area

Study design

Study Population

HBsAg, n (%)

Patients’ characterization and evaluation systema

References

1984

A.Ababa

Prospective longitudinal

304

30(9.9)

Patients with acute or chronic hepatitis, some with malignant liver disease, mainly hepatocellular carcinoma (HCC)

[45]

1989

A.Ababa

Consecutive hospital patients

334

91(27.2)

Based on clinical and histological diagnostic criteria; patients with chronic hepatitis (n = 114), cirrhosis (n = 208) and hepatocellular carcinoma (n = 112)

[46]

1991

North Ethiopia

Epidemic outbreak

423

54(12.8)

Icteric patients hospitalized during HEV

[47]

1992

A.Ababa

Consecutive hospital patients

110

22(20.0)

Consecutive acute hepatitis patients and 19 pregnant women who had HEV infection

[48]

1995

A.Ababa

Consecutive hospital patients

238

65(27.3)

Patients with chronic hepatitis (n = 14), cirrhotic (n = 156) and HCC (n = 68)

[49]

2011

A.Ababa

Prospective consecutive hospital patients

120

43(35.8)

Patients with chronic liver disease based on clinical history, ultrasound, and impaired liver function tests.

[44]

2011

Gondar

Retrospective

2684

386(14.4)

Five year retrospective study on clinically suspected hepatitis patients from different wards of Gondar hospital

[50]

2013

Bale Robe

Retrospective

358

80(22.3)

All patients with chronic hepatitis

[51]

  1. aThe clinical diagnostic criteria for grouping patients as chronic liver disease patients were based on the presence of patient history of either clinical signs like ascites, hepatomegaly, and splenomegaly with other clinical features including jaundice, palmar erythema, clubbing, edema, axillary and pubic hair loss, Spider nevi, flapping tremors, drowsiness, confusion and coma. Ultrasound showing coarse hepatic texture, changes in liver size, increased portal vein diameter, and splenomegaly. Impaired liver function tests, including raised level of alanine aminotransferase (ALT)