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Table 1 Socio-demographic and clinical characteristics by HCV serostatus at postnatal cohort enrolment

From: HCV co-infection and markers of liver injury and fibrosis among HIV-positive childbearing women in Ukraine: results from a cohort study

  Total (n = 2050) HCV antibody negative (n = 1383) HCV antibody positive (n = 667) p value
  n (%) or median [IQR]  
Age (n = 2047) (years) 27.7
[24.6, 31.3]
27.1
[24.1, 30.6]
29.1
[26.2, 32.6]
p < 0.01
Age at leaving full-time education (n = 1429)a     
  ≤ 16 years 331 (23) 159 (17) 172 (34) p < 0.01
 17–18 years 378 (26) 249 (27) 129 (25)  
  ≥ 19 years 720 (50) 515 (56) 205 (41)  
History of IDU (n = 1859)     
 No 1461 (79) 1128 (93) 333 (51) p < 0.01
 Yes 398 (21) 84 (7) 314 (49)  
Ever had an IDU sex partner (n = 1765)     
 No 1416 (80) 1025 (87) 391 (66) p < 0.01
 Yes 349 (20) 149 (13) 200 (34)  
History of imprisonment (n = 1930)     
 No 1862 (96) 1274 (99) 588 (92) p < 0.01
 Yes 68 (4) 16 (1) 52 (8)  
Timing of HIV diagnosis (n = 1873)a     
 Before most recent pregnancy 701 (37) 398 (32) 303 (48) p < 0.01
 During most recent pregnancy 1172 (63) 842 (68) 330 (52)  
CD4 count (n = 1918), (cells/mm3, median [IQR]) 452 [324, 604] 460 [335, 609] 426 [299, 591] p < 0.01
CD4 count (n = 1918)     
  ≤ 350 cells/mm3 566 (30) 356 (28) 210 (33) p = 0.03
 351-500 cells/mm3 582 (30) 395 (31) 187 (30)  
  > 500 cells/mm3 770 (40) 538 (42) 232 (37)  
WHO stage (n = 2041)     
 Stage 1 1424 (70) 1065 (77) 359 (54) p < 0.01
 Stage 2 269 (13) 145 (11) 124 (19)  
 Stage 3 267 (13) 124 (9) 143 (21)  
 Stage 4 81 (4) 41 (3) 40 (6)  
On ART (n = 2029)     
 No 1454 (72) 1012 (74) 442 (67) p < 0.01
 Yes 575 (28) 357 (26) 218 (33)  
Hepatitis B co-infection (n = 1955)     
 No 1626 (83) 1170 (86) 456 (76) p < 0.01
 Yes 329 (17) 184 (14) 145 (24)  
Smoking history (n = 2021)     
 Never smoked 578 (29) 460 (34) 118 (18) p < 0.01
 Past smoker 484 (24) 364 (27) 120 (18)  
 Current smoker, <15 cigarettes /day 417 (21) 304 (22) 113 (17)  
 Current heavy smoker, ≥15 cigarettes /day 440 (22) 176 (13) 264 (40)  
 Current smoker, cigarettes/day not reported 102 (5) 57 (4) 45 (7)  
  1. aAvailable for women with matched pregnancy data from the ECS only