Frequency of empiric antibiotic de-escalation in an acute care hospital with an established Antimicrobial Stewardship Program

Table 3 Patient mortality and length of stay with de-escalation

Patient Characteristics	Antibiotic regimen de-escalated n = 151 (%)	Antibiotic regimen not de-escalated n = 89 (%)	Odds Ratio (95% CI)	p-value
Mortality	13 (9)	21 (24)	0.31 (0.14–0.65)	0.002
Modified Mortality^a	13 (9)	9 (10)	0.84 (0.34–2.05)	NS
Median Length of Stay^b(days)	6	10	N/A	0.0003

^aModified Mortality: considers only patients who survived past day 3 and were subsequently eligible for antibiotic de-escalation at 72 h
^bOverall Median LOS was 7 with an Interquartile Range of 4–13

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