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Table 3 Patient mortality and length of stay with de-escalation

From: Frequency of empiric antibiotic de-escalation in an acute care hospital with an established Antimicrobial Stewardship Program

Patient Characteristics Antibiotic regimen de-escalated
n = 151 (%)
Antibiotic regimen not de-escalated
n = 89 (%)
Odds Ratio (95% CI) p-value
Mortality 13 (9) 21 (24) 0.31 (0.14–0.65) 0.002
Modified Mortalitya 13 (9) 9 (10) 0.84 (0.34–2.05) NS
Median Length of Stayb(days) 6 10 N/A 0.0003
  1. aModified Mortality: considers only patients who survived past day 3 and were subsequently eligible for antibiotic de-escalation at 72 h
  2. bOverall Median LOS was 7 with an Interquartile Range of 4–13