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Table 2 Seroprevalence of positive measles antibodies (p), critical prevalence of antibodies associated with herd immunity (pc) and establishment of herd immunity (HI) - comparing worst, best and absolute case scenario

From: Serological assessment of the establishment of herd immunity against measles in a health district in Malaysia

Characteristics Establishment of herd immunity (HI)
Worst Casea (n = 1541) Best Caseb (n = 1541) Absolute Casec (n = 1447)
p (%) (95% CI) pc (%) (range) HI p (%) (95% CI) pc (%) (range) HI p (%) (95% CI) pc (%) (range) HI
Total 87.0 (85.0–89.0) 89.4 (87.9–90.8) - 93.0 (92.0–94.0) 89.1 (87.6–0.5) + 93.0 (91.0–94.0) 89.1 (87.6–90.5) +
Age (year)
 6–9 90.0 (87.0–94.0) 89.2 (87.4–90.7) + 95.0 (92.0–97.0) 89.0 (87.6–90.5) + 95.0 (92.0–97.0) 89.0 (87.6–90.5) +
 15 – 24 74.0 (70–78) 90.4 (88.9–91.8) - 85.0 (82.0–89.0) 89.5 (88.0–90.9) - 84.0 (80.0–87.0) 89.5 (87.6–90.5) -
 45–54 94.0 (92.0–96.0) 89.0 (87.6–90.5) + 97.0 (96.0 – 98.0) 88.9 (87.5–90.4) + 97.0 (96.0–98.0) 88.9 (87.5–90.4) +
Gender
 Male 85.0 (83.0–88.0) 89.5 (88.0–90.9) - 92.0 (90.0–94.0) 89.1 (87.7–90.6) + 92.0 (89.0–94.0) 89.1 (87.7–90.6) +
 Female 88.0 (86.0–91.0) 89.3 (87.9–90.7) - 94.0 (92.0–96.0) 89.0 (87.6–90.5) + 94.0 (92.0–95.0) 89.0 (87.6–90.5) +
Ethnicity
 Malay 86.0 (83.0–88.0) 89.4 (87.9–90.8) - 92.0 (91.0–94.0) 89.1 (87.7–90.6) + 92.0 (90.0–94.0) 89.1 (87.7–90.6) +
 Chinese 90.0 (85.0–94.0) 89.2 (87.8–90.7) + 93.0 (90.0–97.0) 89.1 (87.6–90.5) + 93.0 (90.0–97.0) 89.1 (87.6–90.5) +
 Indian 89.0 (85.0–92.0) 89.3 (87.8–90.7) - 94.0 (92.0–97.0) 89.0 (87.6–90.5) + 94.0 (92.0–97.0) 89.0 (87.6–90.5) +
 Others 93.0 (83.0–103.0) 89.1 (87.6–90.5) + 96.0 (89.0–104.0) 88.8 (87.4–90.4) + 96.0 (89.0–104.0) 88.8 (87.4–90.4) +
  1. aAssuming all indeterminate results are negative,b Assuming all indeterminate results are positive, cIneterminate result are not presented
  2. (p) Seroprevalence of positive measles antibodies; (pc) Critical prevalence of antibodies associated with herd immunity
  3. (HI) Herd Immunity; + Herd Immunity Established (p > mean pc); - Herd Immunity Not Established (p < mean pc)
  4. Calcualted using Critical Prevalence of Protected Individuals, Ic (%) = 92.5 (91–94)