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Table 1 Logistic regression estimates of the unadjusted and adjusted odds ratios of prevalent tuberculosis in the Zambian study sites

From: The association of hyperglycaemia with prevalent tuberculosis: a population-based cross-sectional study

Characteristic

Total number (%)

Number (%) with prevalent TB

Unadjusted OR (95% CI)

P-value#

Adjusteda OR (95% CI)

P-value#

Overall

27,800 (100)

144 (0 · 5)

-

-

-

-

Random blood glucose concentration (mmol/L)

<5.6

14,741 (53.0)

67 (0.5)

1

0.029 (test for linear trend p = 0.017; test for departure from trend p = 0.164)

1

0.011 (test for linear trend p = 0.006; test for departure from trend p = 0.141)

5.6–6.9

8,628 (31.0)

42 (0.5)

1.06 (0.72–1.56)

1.13 (0.75–1.71)

7.0–8.9

3,447 (12.4)

24 (0.7)

1.51 (0.94–2.41)

1.6 (0.96–2.66)

9.0–11.0

579 (2.1)

9 (1.6)

3.44 (1.7–6.96)

4.31 (2.07–8.97)

>11.0

405 (1.5)

2 (0.5)

1.06 (0.26–4.35)

0.97 (0.13–7.14)

Age (years)

18–24

9,733 (35 · 4)

37 (0 · 4)

1

0 · 004

1

0 · 390

25–29

4,665 (17 · 0)

32 (0 · 7)

1 · 79 (1 · 11–2 · 88)

1.27 (0.75–2.16)

30–34

3,438 (12 · 5)

28 (0 · 8)

2 · 15 (1 · 31–3 · 52)

1.42 (0.83–2.46)

35–39

2,381 (8 · 7)

16 (0 · 7)

1 · 79 (0 · 99–3 · 24)

1.09 (0.57–2.09)

40–49

3,173 (11 · 5)

20 (0 · 6)

1 · 67 (0 · 97–2 · 89)

1.04 (0.56–1.92)

50–59

2,113 (7 · 7)

7 (0 · 3)

0 · 87 (0 · 39–1 · 96)

0.74 (0.32–1.72)

60+

1,998 (7 · 3)

4 (0 · 2)

0 · 55 (0 · 20–1 · 55)

0.49 (0.16–1.45)

Sex

Male

9,265 (33 · 3)

64 (0 · 7)

1

0 · 003

1

0 · 008

Female

18,535 (66 · 7)

80 (0 · 4)

0 · 60 (0 · 43–0 · 84)

0.59 (0.41–0.87)

HIV status

Negative

21,103 (82 · 5)

72 (0 · 3)

1

<0 · 001

1

<0 · 001

Positive

4,465 (17 · 5)

66 (1 · 5)

4 · 22 (3 · 00–5 · 92)

3.57 (2.44–5.23)

Body Mass Index (weight(kg)/height2(m))

Healthy weight (18.5–24.9)

16,497 (64.2)

95 (0.6)

1

<0.001

1

<0.001

Underweight (<18.5)

2,604 (10.1)

27 (1.0)

1.87 (1.22–2.89)

1.70 (1.09–2.65)

Overweight (25–29.9)

4,402 (17.1)

13 (0.3)

0.49 (0.27–0.88)

0.56 (0.3–1.05)

Obese (≥30)

2,214 (8.6)

1 (0.1)

0.07 (0.01–0.53)

0.10 (0.01–0.76)

Region

Rural, low ARTI

7,712 (27 · 7)

24 (0 · 3)

1

0 · 012

1

0 · 002

Urban (non-Lusaka), low ARTI

6,033 (21 · 7)

34 (0 · 6)

1 · 83 (1 · 02–3 · 29)

2.13 (1.12–4.04)

Urban (non-Lusaka), high ARTI

5,158 (18 · 6)

22 (0 · 4)

1 · 39 (0 · 74–2 · 63)

1.59 (0.81–3.14)

Lusaka, high ARTI

8,897 (32 · 0)

64 (0 · 7)

2 · 34 (1 · 37–3 · 98)

2.88 (1.62–5.11)

  1. TB tuberculosis, OR odds ratio, CI confidence interval, ARTI annual risk of infection; All analyses accounted for the two-stage clustered sampling design through the use of a logistic regression model with random effects for enumeration area and inclusion of region as a fixed effect, with each region including 4 communities; #Likelihood ratio tests; a23,414 participants included in analysis (299 missing data for age, 2,083 for BMI, 2,232 for HIV status), adjusted for variables shown plus household socioeconomic position and education