Table 4 DALYs averted per country and scenario and incremental cost-effectiveness ratios (societal perspective), if drug price is 1USD per day

Current 6mo Rx

DALY averted, mean (SD)

9.97 (0.23)

8.26 (0.18)

DALY averted, median (2.5–97.5)

9.97 (9.52–10.42)

8.26 (7.92–8.61)

New 4mo Rx

DALY averted, mean (SD)

10.0 (0.23)

8.37 (0.18)

DALY averted, median (2.5–97.5)

9.99 (9.55–10.43)

8.37 (8.04–8.72)

mean difference (%)

0.02 (0.07)

0.11 (0.03)

ICER, median (2.5–97.5)

CS (CS-26,065)

16.9 (CS-897)

ICER, calculated mean

CS

13.6

GDP per capita

Current 6mo Rx

DALY averted, mean (SD)

16.50 (0.51)

14.68 (0.51)

DALY averted, median (2.5–97.5)

16.52 (15.54–17.48)

14.67 (13.74–15.65)

New 4mo Rx

DALY averted, mean (SD)

16.54 (0.51)

15.18 (0.51)

DALY averted, median (2.5–97.5)

16.56 (15.55–17.54)

15.16 (14.25–16.16)

mean difference (%)

0.04 (0.06)

0.50 (0.08)

ICER, median (2.5–97.5)

CS (CS-116,251)

CS (CS-362)

ICER, calculated mean

CS

CS

GDP per capita

Current 6mo Rx

DALY averted, mean (SD)

16.19 (0.53)

16.17 (0.51)

DALY averted, median (2.5–97.5)

16.20 (15.20–17.21)

16.16 (15.17–17.15)

New 4mo Rx

DALY averted, mean (SD)

16.21 (0.53)

16.20 (0.51)

DALY averted, median (2.5–97.5)

16.22 (15.19–17.24)

16.18 (15.19–17.15)

mean difference (%)

0.02 (0.06)

0.02 (0.06)

ICER, median (2.5–97.5)

164 (CS-9,075)

129 (CS-8,824)

ICER, calculated mean

1,472

1,220

GDP per capita

Current 6mo Rx

DALY averted, mean (SD)

13.66 (0.36)

12.97 (0.36)

DALY averted, median (2.5–97.5)

13.66 (12.98–14.35)

12.96 (12.31–13.65)

New 4mo Rx

DALY averted, mean (SD)

13.68 (0.36)

13.00 (0.36)

DALY averted, median (2.5–97.5)

13.67 (12.99–14.36)

12.99 (12.32–13.70)

mean difference (%)

0.02 (0.04)

0.03 (0.05)

ICER, median (2.5–97.5)

CS (CS-12,252)

39 (CS-3,937)

ICER, calculated mean

CS

161

GDP per capita