|
Microbiological outcome at TOC visit
|
Clinical outcome at LFU visit
|
% Difference in relapse between persisted and eradicated (95% CI)
|
|---|
|
Sustained
|
Indeterminate
|
Relapse
|
|---|
|
Eradicated, n/N (%)
|
225/229 (98.3)
|
1/229 (0.4)
|
3/229 (1.3)
|
17.2 (8.7–29.6)
|
|
Persisted, n/N (%)
|
42/54 (77.8)
|
2/54 (3.7)
|
10/54 (18.5)
|
- CI confidence interval, LFU late follow-up, ME microbiologically evaluable, TOC test-of-cure
- Four patients had 2 Enterobacteriaceae isolates identified at baseline and a clinical response of cure at the TOC visit. These patients were counted once for this analysis by assignment to the “persisted at TOC group” if 1 isolate persisted (1 patient) and to the “eradicated at TOC group” if both isolates were eradicated (3 patients). All 4 experienced sustained response at the LFU visit
