Table 1 Demographic and clinical characteristics of patients with positive isolates for XDRAB
Variable | No of patients (%) n = 8 |
|---|---|
Age (years), mean ± SD | 64.5 ± 14.7 |
Male % | 4 (50) |
Intrinsic Risk Factors | |
Tabagism | 3 (37.5) |
Diabetes Mellitus | 2 (25) |
Chronic Obstructive Pulmonary Disease | 2 (25) |
Previous hospitalization | 2 (25) |
Chronic kidney disease | 1 (12.5) |
Malignancy | 1 (12.5) |
Politrauma | 1 (12.5) |
Use of steroid | 7 (87.5) |
Diagnoses upon admission | |
Coronary Artery Disease | 2 (25) |
Respiratory Failure | 1 (12.5) |
Pulmonary Embolism | 1 (12.5) |
Pneumonia | 1 (12.5) |
Cancer | 1 (12.5) |
Shock | 1 (12.5) |
Fracture/Politrauma | 1 (12.5) |
Site of isolates | |
Bronchoalveolar lavage | 6 (37.5) |
Endotracheal aspirate | 4 (25) |
Central venous blood | 2 (12.5) |
Sputum culture | 2 (12.5) |
Peripheral venous blood | 1 (6.25) |
Rectal swab | 1 (6.25) |
Device | |
Endotracheal tube | 8 (100) |
Central venous catheter | 8 (100) |
Pleural dreinage | 2 (25) |
Total Parental Nutrition | 5 (62.5) |
Previous use of antibiotic in the preceding 90 days | |
β-lactam | 1 (12.5) |
β-lactam plus another antibiotic | 1 (12.5) |
β-lactam plus at least two other categories of antibiotics | 6 (75) |
Hospital stay before acquisition of XDRAB (days) | 8.3 ± 8.8 |
ICU stay before acquisition of XDRAB (days) | 9.4 ± 8.8 |
Clinical significance | |
Ventilator associated Pneumonia | 6 (75) |
Central venous catheter infection | 2 (25) |
Outcome | |
In-hospital mortality | 4 (50) |