Quality assurance of human papillomavirus (HPV) testing in the implementation of HPV primary screening in Norway: an inter-laboratory reproducibility study

Table 4 Agreement of HPV test results between the four laboratories including HPV genotype information

Test results compared	Overall percentage agreement	Positive percentage agreement	k value (95% CI)	Number of samples
Multiple genotypes taken into consideration	93.8	78.7	0.93 (0.91–0.96)	499
Highest risk genotype taken into consideration	94.4	82.5	0.94 (0.91–0.96)	499

Calculations were performed both with and without taking multiple infections into consideration. For calculation not considering multiple infections, HPV type category with highest oncogenic potential was the deciding factor; HPV16>HPV18>HR-HPV

ISSN: 1471-2334