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Table 2 Yield of smear microscopy versus Xpert among culture confirmed tuberculosis patients (n =96)

From: Diagnostic performance of smear microscopy and incremental yield of Xpert in detection of pulmonary tuberculosis in Rwanda

 

Xpert

Sensitivity of SM % (95 %, CI)

Incremental sensitivity of Xpert % (95 %,CI)

Positive

Negative

Overall SM at all HF

n = 96

positive

46

3

51.0 (40.6–61.4)

32.3 (23.1–42.6)

negative

31

16

SM in all HIV positive

n = 28

positive

10

1

39.3 (21.5–59.4)

35.7 (18.6–55.9)

negative

10

7

SM in all HIV negative

n = 68

positive

36

2

55.9 (43.3–67.9)

30.9 (20.2–43.3)

negative

21

9

SM at all PL

n = 76

positive

34

3

48.7 (37.0–60.4)

32.9 (22.5–44.6)

negative

25

14

SM at all IL

n = 20

positive

12

0

60.0 (36.1–80.9)

30.0 (11.9–54.3)

negative

6

2

SM at ZN PL

n = 49

positive

24

3

55.1 (40.2–69.3)

32.7 (19.9–47.5)

negative

16

6

SM at LED-FM PL

n = 27

positive

10

0

37.0 (19.4–57.6)

33.3 (16.5–54.0)

negative

9

8

SM at ZN IL

n = 12

positive

7

0

58.3 (27.7–84.8)

25.0 (5.5–57.2)

negative

3

2

SM at LED-FM IL

n = 8

positive

5

0

62.5 (24.5–91.5)

37.5 (8.5–75.5)

negative

3

0

  1. LED-FM light emitting diode fluorescence microscopy; ZN Ziehl Nelsen Xpert: Xpert MTB/RIF test; HIV human immunodeficiency virus; CI confidence interval; SM smear microscopy; IL intermediate laboratories; PL peripheral laboratories; SM smear microscopy