Table 2 Clinical and microbiologic characteristics of patients with tuberculosis caused by Mycobacterium bovis or Mycobacterium tuberculosis, Mexico City, 2000–2015
Etiological agent | |||
|---|---|---|---|
Characteristic | M. bovis (n = 161) | M. tuberculosis (n = 372) | p a |
Anatomical site of isolation | |||
Pulmonary | 58/161 (36) | 196/372 (52.6) | <0.001 |
Extrapulmonary | 67/161 (41.6) | 112/372 (30.1) | 0.01 |
Pulmonary and Extrapulmonary | 36/161 (22.3) | 64/372 (17.2) | 0.16 |
Primary site of isolation (Restricted to pulmonary cases with and extrapulmonary involvements casesb) | |||
Abdominalc | 7/36 (19.4) | 22/64 (34.3) | 0.11 |
Genitourinary | 16/36 (44.4) | 22/64 (34.3) | 0.31 |
Central Nervous System | 10/36 (27.7) | 9/64 (14) | 0.093 |
Lymph node | 0/36 (0) | 1/64 (1.5) | – |
Skin, joint, bone, and soft tissue | 3/36 (8.3) | 2/64 (3.1) | 0.25 |
Blood, bone marrow, liver, and spleen | 0/36 (0) | 8/64 (12.5) | – |
Primary site of isolation (Restricted to extrapulmonary casesd) | |||
Abdominalc | 22/67 (32.8) | 12/112 (10.7) | <0.001 |
Genitourinary | 9/67 (13.4) | 26/112 (23.2) | 0.11 |
Central Nervous System | 14/67 (20.9) | 17/112 (15.1) | 0.32 |
Lymph node | 15/67 (22.3) | 37/112 (33) | 0.12 |
Skin, joint, bone, and soft tissue | 4/67 (5.9) | 13/112 (11.6) | 0.21 |
Blood, bone marrow, liver, and spleen | 3/67 (4.4) | 7/112 (6.2) | 0.61 |
Primary site of isolation (Restricted to pulmonary cases with and extrapulmonary involvement casesd) | |||
Abdominalc | 7/36 (19.4) | 22/64 (34.3) | 0.11 |
Genitourinary | 16/36 (44.4) | 22/64 (34.3) | 0.31 |
Central Nervous System | 10/36 (27.7) | 9/64 (14) | 0.093 |
Lymph node | 0/36 (0) | 1/64 (1.5) | – |
Skin, joint, bone, and soft tissue | 3/36 (8.3) | 2/64 (3.1) | 0.25 |
Blood, bone marrow, liver, and spleen | 0/36 (0) | 8/64 (12.5) | – |
Symptom onset to diagnosis, days, median (IQR) | 63 (32–154) | 90 (34–197) | 0.089e |
Presenting symptoms | |||
Fever | 127/159 (79.8) | 254/364 (69.7) | 0.019 |
Weight loss | 72/159 (45.2) | 181/364 (49.7) | 0.38 |
Cough | 60/159 (37.7) | 195/364 (53.5) | 0.001 |
Haemoptysis | 5/159 (3.1) | 29/364 (7.9) | 0.039 |
Gastrointestinalf | 71/159 (44.6) | 117/364 (32.3) | 0.007 |
Neurological | 30/159 (18.8) | 63/364 (17.3) | 0.67 |
Genitourinary | 10/159 (6.2) | 29/364 (7.9) | 0.49 |
Primary multidrug resistanceg | 1/161 (0.6) | 6/372 (1.6) | 0.35 |
Mean TST induration, mm, (IQR) | 9.6 (0–18) | 14 (0–25) | 0.02e |
≥5 mm | 30/76 (39.4) | 91/172 (52.9) | 0.051 |
≥10 mm | 29/76 (38.1) | 91/172 (52.9) | 0.032 |
≥15 mm | 23/76 (30.2) | 79/172 (45.9) | 0.021 |