Skip to main content

Table 2 Clinical and microbiologic characteristics of patients with tuberculosis caused by Mycobacterium bovis or Mycobacterium tuberculosis, Mexico City, 2000–2015

From: Human tuberculosis caused by Mycobacterium bovis: a retrospective comparison with Mycobacterium tuberculosis in a Mexican tertiary care centre, 2000–2015

  Etiological agent  
Characteristic M. bovis
(n = 161)
M. tuberculosis
(n = 372)
p a
Anatomical site of isolation
 Pulmonary 58/161 (36) 196/372 (52.6) <0.001
 Extrapulmonary 67/161 (41.6) 112/372 (30.1) 0.01
 Pulmonary and Extrapulmonary 36/161 (22.3) 64/372 (17.2) 0.16
Primary site of isolation (Restricted to pulmonary cases with and extrapulmonary involvements casesb)
 Abdominalc 7/36 (19.4) 22/64 (34.3) 0.11
 Genitourinary 16/36 (44.4) 22/64 (34.3) 0.31
 Central Nervous System 10/36 (27.7) 9/64 (14) 0.093
 Lymph node 0/36 (0) 1/64 (1.5)
 Skin, joint, bone, and soft tissue 3/36 (8.3) 2/64 (3.1) 0.25
 Blood, bone marrow, liver, and spleen 0/36 (0) 8/64 (12.5)
Primary site of isolation (Restricted to extrapulmonary casesd)
 Abdominalc 22/67 (32.8) 12/112 (10.7) <0.001
 Genitourinary 9/67 (13.4) 26/112 (23.2) 0.11
 Central Nervous System 14/67 (20.9) 17/112 (15.1) 0.32
 Lymph node 15/67 (22.3) 37/112 (33) 0.12
 Skin, joint, bone, and soft tissue 4/67 (5.9) 13/112 (11.6) 0.21
 Blood, bone marrow, liver, and spleen 3/67 (4.4) 7/112 (6.2) 0.61
Primary site of isolation (Restricted to pulmonary cases with and extrapulmonary involvement casesd)
 Abdominalc 7/36 (19.4) 22/64 (34.3) 0.11
 Genitourinary 16/36 (44.4) 22/64 (34.3) 0.31
 Central Nervous System 10/36 (27.7) 9/64 (14) 0.093
 Lymph node 0/36 (0) 1/64 (1.5)
 Skin, joint, bone, and soft tissue 3/36 (8.3) 2/64 (3.1) 0.25
 Blood, bone marrow, liver, and spleen 0/36 (0) 8/64 (12.5)
 Symptom onset to diagnosis, days, median (IQR) 63 (32–154) 90 (34–197) 0.089e
Presenting symptoms
 Fever 127/159 (79.8) 254/364 (69.7) 0.019
 Weight loss 72/159 (45.2) 181/364 (49.7) 0.38
 Cough 60/159 (37.7) 195/364 (53.5) 0.001
 Haemoptysis 5/159 (3.1) 29/364 (7.9) 0.039
 Gastrointestinalf 71/159 (44.6) 117/364 (32.3) 0.007
 Neurological 30/159 (18.8) 63/364 (17.3) 0.67
 Genitourinary 10/159 (6.2) 29/364 (7.9) 0.49
Primary multidrug resistanceg 1/161 (0.6) 6/372 (1.6) 0.35
Mean TST induration, mm, (IQR) 9.6 (0–18) 14 (0–25) 0.02e
 ≥5 mm 30/76 (39.4) 91/172 (52.9) 0.051
 ≥10 mm 29/76 (38.1) 91/172 (52.9) 0.032
 ≥15 mm 23/76 (30.2) 79/172 (45.9) 0.021
  1. Data are n/N (%) of cases, unless otherwise indicated. n values across categories might be less than the counts in the column headings due to missing data
  2. IQR Interquartile range, TST tuberculin skin test
  3. ap values were determined by the two-sample test of proportion or the χ2 test, as appropriate
  4. bRestricted to cases with extrapulmonary disease only
  5. cGastrointestinal, peritoneal, and faecal samples
  6. dRestricted to cases with both pulmonary and extrapulmonary disease
  7. ep value was determined by the Mann–Whitney U test
  8. fDiarrhoea, vomiting, and abdominal pain
  9. gResistance to at least both isoniazid and rifampicin