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Table 1 Sociodemographic characteristics and comorbidities of patients with tuberculosis caused by Mycobacterium bovis or Mycobacterium tuberculosis, Mexico City, 2000–2015

From: Human tuberculosis caused by Mycobacterium bovis: a retrospective comparison with Mycobacterium tuberculosis in a Mexican tertiary care centre, 2000–2015

  Etiological agent  
Characteristic M. bovis
(n = 161)
M. tuberculosis
(n = 372)
p a
Age, years, median (IQR) 38 (29–52) 49 (33–64) <0.001b
Sex (female) 66/161 (40.9) 164/372 (44) 0.5
Healthcare worker 5/151 (3.3) 19/360 (5.2) 0.33
Farm worker 5/151 (3.3) 26/360 (7.2) 0.09
Low socioeconomic status 17/161 (10.5) 62/372 (16.6) 0.068
BCG-vaccinated 82/118 (69.4) 179/261 (68.5) 0.86
Contact with TB-infected people 18/139 (12.9) 67/335 (20) 0.069
Resides in a non-accredited zone for bovine-TB eradicationc 140/159 (88) 303/370 (81.8) 0.078
Alcohol intake ≥ 40 g/day 9/152 (5.9) 36/354 (10.1) 0.12
Smoker (present) 71/153 (46.4) 147/356 (41.2) 0.28
HIV coinfection 43/161 (26.7) 79/372 (21.2) 0.16
CD4 count ≤200 cells/mm3 31/35 (88.5) 60/67 (89.5) 0.87
Diabetes mellitus 23/161 (14.2) 84/372 (22.5) 0.028
Connective tissue diseased 29/161 (18) 43/372 (11.5) 0.045
Solid organ transplant recipient 4/161 (2.4) 8/372 (2.1) 0.81
Charlson comorbidity index ≥3 72/161 (44.7) 150/372 (40.3) 0.34
Previous TB 2/161 (1.2) 14/372 (3.7) 0.11
Glucocorticoid usee 46/161 (28.5) 54/372 (14.5) <0.001
  1. Data are n/N (%) of cases, unless otherwise indicated. n values across categories might be less than the counts in the column headings due to missing data
  2. IQR Interquartile range, TB Tuberculosis, HIV Human immunodeficiency virus, BCG Bacillus Calmette-Guérin
  3. ap values were determined by the χ2 test
  4. bp value was determined by Student’s t-test
  5. cAs determined by SENASICA
  6. dSystemic lupus erythematosus, rheumatoid arthritis, Sjögren syndrome, dermatomyositis, ankylosing spondylitis, mixed connective tissue disease, systemic sclerosis
  7. e ≥ 15 mg/d of prednisone or equivalent dose of steroids for 1 month or more in the year prior to TB diagnosis