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Table 4 Diagnostic Performance of RDT using Microscopy and PCR as gold standards for the detection of malaria parasites in febrile children

From: Prevalence of malaria, typhoid, toxoplasmosis and rubella among febrile children in Cameroon

 

Sensitivity % (95 % CI)

Specificity % (95 % CI)

NPV % (95 % CI)

PPV % (95 % CI)

Cohen’s Kappa

Degree of agreement (%)

P-value

Microscopy vs RDT

75.98 [69.2–81.65]

100 [97.3–100]

76.0 [69.2–81.7]

100 [97.3–100]

.73

86.35 [82.1–89.7]

0.000

RDT vs PCR

81 [75.3–85.6]

100 [96.1–100]

69.12 [60.9–76.3]

100 [98.0–100]

.72

86.7 [82.5–89.9]

0.000

  1. PPV; Positive predictive value, NPV; Negative predictive value, RDT; Rapid diagnostic test, CI Confidence Interval, PCR; Polymerase chain reaction. The 2 -Tailed P exact Fisher Test was used to compare RDT with microscopy and PCR