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Table 4 Diagnostic Performance of RDT using Microscopy and PCR as gold standards for the detection of malaria parasites in febrile children

From: Prevalence of malaria, typhoid, toxoplasmosis and rubella among febrile children in Cameroon

  Sensitivity % (95 % CI) Specificity % (95 % CI) NPV % (95 % CI) PPV % (95 % CI) Cohen’s Kappa Degree of agreement (%) P-value
Microscopy vs RDT 75.98 [69.2–81.65] 100 [97.3–100] 76.0 [69.2–81.7] 100 [97.3–100] .73 86.35 [82.1–89.7] 0.000
RDT vs PCR 81 [75.3–85.6] 100 [96.1–100] 69.12 [60.9–76.3] 100 [98.0–100] .72 86.7 [82.5–89.9] 0.000
  1. PPV; Positive predictive value, NPV; Negative predictive value, RDT; Rapid diagnostic test, CI Confidence Interval, PCR; Polymerase chain reaction. The 2 -Tailed P exact Fisher Test was used to compare RDT with microscopy and PCR