Skip to main content

Table 4 Test characteristics of the RT hrHPV and HC2 tests for detection of high grade cervical disease (CIN3+)

From: Study-based evaluation of the Abbott RealTime High Risk HPV test in comparison to the HC2 HR HPV test in women aged ≥30 years using residual LBC ThinPrep specimens

  Relative sensitivity CIN2+ Relative sensitivity CIN3+ Relative specificity <CIN2 PPV CIN2+ NPV < CIN2
% 95 % CI % 95 % CI % 95 % CI % 95 % CI % 95 % CI
HR HC2 98.2 89.4–99.9 97.9 97.5–99.9 79.8 77.5–81.8 16.5 12.8–21.0 99.9 99.4–100
Abbott RT 94.7 84.5–98.6 93.8 81.8–98.4 81.1 78.9–83.1 16.9 13.1–21.6 99.7 99.2–99.9
Abbott RT HPV16 56.1 42.4–66.9 60.4 45.3–73.9 75.0 52.9–89.4 84.2 59.4–68.1 41.9 27.4–57.8
Abbott RT HPV18 7.0 2.3–17.8 6.3 1.6–18.2 77.5 75.2–79.6 50 17.4–82.6 27.4 17.9–39.3
Abbott RT non 16/18 33.3 21.7–47.2 29.2 17.4–44.3 54.2 33.2–73.8 63.3 43.9–79.5 25.5 14.8–39.9
  1. +: and worse; CI Confidence interval