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Table 4 Test characteristics of the RT hrHPV and HC2 tests for detection of high grade cervical disease (CIN3+)

From: Study-based evaluation of the Abbott RealTime High Risk HPV test in comparison to the HC2 HR HPV test in women aged ≥30 years using residual LBC ThinPrep specimens

 

Relative sensitivity CIN2+

Relative sensitivity CIN3+

Relative specificity <CIN2

PPV CIN2+

NPV < CIN2

%

95 % CI

%

95 % CI

%

95 % CI

%

95 % CI

%

95 % CI

HR HC2

98.2

89.4–99.9

97.9

97.5–99.9

79.8

77.5–81.8

16.5

12.8–21.0

99.9

99.4–100

Abbott RT

94.7

84.5–98.6

93.8

81.8–98.4

81.1

78.9–83.1

16.9

13.1–21.6

99.7

99.2–99.9

Abbott RT HPV16

56.1

42.4–66.9

60.4

45.3–73.9

75.0

52.9–89.4

84.2

59.4–68.1

41.9

27.4–57.8

Abbott RT HPV18

7.0

2.3–17.8

6.3

1.6–18.2

77.5

75.2–79.6

50

17.4–82.6

27.4

17.9–39.3

Abbott RT non 16/18

33.3

21.7–47.2

29.2

17.4–44.3

54.2

33.2–73.8

63.3

43.9–79.5

25.5

14.8–39.9

  1. +: and worse; CI Confidence interval