Study-based evaluation of the Abbott RealTime High Risk HPV test in comparison to the HC2 HR HPV test in women aged ≥30 years using residual LBC ThinPrep specimens

Table 3 HPV genotyping of discordant samples with the LiPA Extra test

HPV Genotype	HPV classification	HC2-ve RT + ve (N)	RT-ve HC2 + ve (N)	Histology CIN3+ (HC2-ve/RT-ve)
HPV 16^a	HR	2	1	0
HPV 18^a	HR	0	3	0
HPV 31^a	HR	0	6	0/2
HPV 33^a	HR	0	0	0
HPV 39^a	HR	0	1	0
HPV 45^a	HR	2	0	0
HPV 51^a	HR	4	3	0
HPV 52^a	HR	0	4	0
HPV 56^a	HR	0	1	0
HPV 58^a	HR	0	1	0
HPV 59^a	HR	1	0	0
HPV 68^a	HR	0	0	0
HPV 53	Intermediate	0	11	0
HPV 66^b	Intermediate	0	1	0
HPV 70	Intermediate	0	2	0
HPV 6	LR	0	1	0
HPV 54	LR	0	1	0
HPV 74		1	1	0
HPVX		0	2	0
HPV DNA -ve		7	5	0
no result (sample failed)		1	3	0
Total		18	47	0/2

^a HC2 and RT target types; ^b RT target type; HC2, Digene Hybrid Capture 2 High-Risk HPV DNA test, RT, Abbott RealTime High Risk HPV Test, HPVX HPV DNA was detected by LiPA, but could not be correlated to a specific type; HR High-risk, LR Low-risk; +ve: positive; −ve: negative; +: and worse

ISSN: 1471-2334