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Table 1 HPV prevalence detected by the RT hrHPV test and the HC2 test in comparison to the liquid based cytology (LBC) results

From: Study-based evaluation of the Abbott RealTime High Risk HPV test in comparison to the HC2 HR HPV test in women aged ≥30 years using residual LBC ThinPrep specimens

LBC

RT + ve % (95 % CI)

HR HC2 + ve % (95 % CI)

κ (95 % CI)

Normal (Pap I/II)

5.4 % (4.2-6.9)

5.6 % (4.3-7.1)

0.78 (0.69-0.87)

ASC-US (Pap IIw)

21.4 % (12.7-33.8)

28.6 % (18.4-41.5)

0.62 (0.38-0.86)

ASC-H, AGC (Pap III)

50.0 % (28.0–72.0)

50.0 % (28.0–72.0)

1 (1.0–1.0)

LSIL, HSIL (Pap IIID)

65.1 % (59.6–70.3)

72.1 % (66.8–76.9)

0.76 (0.68–0.84)

HSIL, CIS (Pap IVa)

94.7 % (82.7–98.6)

100 % (90.8–100)

1

HSIL, CIS, Micro (IVb)

100 % (34.2–100)

100 % (34.2–100)

1

Micro, Invasive (PapV)

100 % (20.6–100)

100 % (20.6–100)

1

HSIL+ (≥Pap IVa)

95.1 % (83.9–98.7)

100 % (91.4–100)

1

AGC+ (≥Pap III)

68.0 % (62.9–72.5)

74.3 % (69.5–78.6)

0.78 (0.70–0.84)

Overall

21.4 % (19.3–23.5)

23.4 % (21.3–25.6)

0.87 (0.84–0.90)

  1. +ve: positive; −ve: negative; +: and worse
  2. 95 % CI for HPV prevalence were calculated using the Wilson Score method