Table 1 Univariate analysis of risk factors for infection-related death in 127 patients with infections caused by CRE

 Age (years) (SD)

55.7(18)

 Age over 60 (%)

57(44.9)

32(38.5)

25(56.8)

1.29(0.99–1.70)

0.03

 Male (%)

88(69.3)

59(71.0)

29(65.9)

0.91(0.68–1.22)

0.34

 ICU (%)

98(77.2)

60(72.3)

38(86.4)

1.29(1.01–1.65)

0.054

 Comorbidities (%)

97(76.4)

67(73.6)

30(83.3)

1.39(1.10–1.75)

0.01

  =1

23(18.1)

19(22.9)

4(9,0)

0.74(0.58–0.94)

0.04

  =2

32(25.2)

17(20.5)

15(34.0)

1.30(0.92–1.85)

0.07

  3 or more

42(33.0)

22(26.5)

20(45.4)

1.37(0.99–1.88)

0.02

 Surgery (%)

59(46.5)

41(49.4)

18(40.9)

0.88(0.69–1.14)

0.23

 Dialyses (%)

45(35.4)

18(21.7)

27(61.4)

1.98(1.36–2.88)

0.0001

 Previous colonization (%)

76(59.8)

50(60.2)

26(59.0)

0.98(0.75–1.27)

0.52

 Pneumonia

52(41.0)

25(30.1)

27(61.4)

1.60(1.18–2.18)

0.0006

 UTI

51(40.2)

39(47.0)

12(27.3)

0.75(0.59–0.96)

0.02

 Bloodstream

9(7.0)

7(8.4)

2(4.5)

0.82(0.56–1.20)

0.33

 Tissue

13(10.2)

10(12.0)

3(6.8)

0.83(0.59–1.15)

0.27

 Abdominal

2(1.6)

2(2.4)

0

0.64(0.56–0.73)

0.42

 Sepsis

28(22.0)

27(32.5)

1(2.3)

0.58(0.48–0.70)

0.0001

 Severe sepsis

21(16.5)

17(20.5)

4(9.0)

0.76(0.59–0.99)

0.07

 Shock

63(49.6)

25(30.1)

38(86.4)

2.28(1.66–3.12)

0.0001

 Lungs

46(36.2)

23(27.7)

23(52.7)

1.48(1.07–2.03)

0.005

 Urine

51(40.2)

39(47.0)

12(27.3)

0.75(0.59–0.96)

0.02

 Blood

21(16.5)

11(13.2)

10(22.7)

1.29(0.84–1.99)

0.13

 Tissue

11 (8.7)

7(8.4)

4(9.1)

1.02(0.64–1.64)

0.56

 Others

8(8.0)

8(9.6)

0

0.63(0.54–0.72)

0.02

 K. pneumoniae

113(89.0)

74(89.2)

39(88.6)

0.98(0.64–1.48)

0.57

 Polymyxin-resistant

27(21.3)

17(20.5)

10(22.7)

1.04(0.75–1.44)

0.46

 Polymicrobial

55(43.3)

34(41.0)

21(47.7)

1.10(0.84–1.42)

0.29

 Co-infection A. baumannii

36(28.3)

22(26.5)

14(31.8)

1.09(0.81–1.47)

0.33

 Co-infection P. aeruginosa

13(10.2)

7(8.4)

6 (13.6)

1.23(0.73–2.08)

0.26

 bla_KPC+

96(75.6)

68(81.9)

28(63.6)

0.68(0.46–1.00)

0.02