|
Characteristics
|
Total (n = 127)
|
Survivors (n = 83)
|
Deaths (n = 44)
|
RR (95 % CI)
|
P
|
|---|
|
Patient related
|
|
Age (years) (SD)
|
55.7(18)
| | | | |
|
Age over 60 (%)
|
57(44.9)
|
32(38.5)
|
25(56.8)
|
1.29(0.99–1.70)
|
0.03
|
|
Male (%)
|
88(69.3)
|
59(71.0)
|
29(65.9)
|
0.91(0.68–1.22)
|
0.34
|
|
ICU (%)
|
98(77.2)
|
60(72.3)
|
38(86.4)
|
1.29(1.01–1.65)
|
0.054
|
|
Comorbidities (%)
|
97(76.4)
|
67(73.6)
|
30(83.3)
|
1.39(1.10–1.75)
|
0.01
|
|
=1
|
23(18.1)
|
19(22.9)
|
4(9,0)
|
0.74(0.58–0.94)
|
0.04
|
|
=2
|
32(25.2)
|
17(20.5)
|
15(34.0)
|
1.30(0.92–1.85)
|
0.07
|
|
3 or more
|
42(33.0)
|
22(26.5)
|
20(45.4)
|
1.37(0.99–1.88)
|
0.02
|
|
Surgery (%)
|
59(46.5)
|
41(49.4)
|
18(40.9)
|
0.88(0.69–1.14)
|
0.23
|
|
Dialyses (%)
|
45(35.4)
|
18(21.7)
|
27(61.4)
|
1.98(1.36–2.88)
|
0.0001
|
|
Previous colonization (%)
|
76(59.8)
|
50(60.2)
|
26(59.0)
|
0.98(0.75–1.27)
|
0.52
|
|
Infection (%)
|
|
Pneumonia
|
52(41.0)
|
25(30.1)
|
27(61.4)
|
1.60(1.18–2.18)
|
0.0006
|
|
UTI
|
51(40.2)
|
39(47.0)
|
12(27.3)
|
0.75(0.59–0.96)
|
0.02
|
|
Bloodstream
|
9(7.0)
|
7(8.4)
|
2(4.5)
|
0.82(0.56–1.20)
|
0.33
|
|
Tissue
|
13(10.2)
|
10(12.0)
|
3(6.8)
|
0.83(0.59–1.15)
|
0.27
|
|
Abdominal
|
2(1.6)
|
2(2.4)
|
0
|
0.64(0.56–0.73)
|
0.42
|
|
Sepsis
|
28(22.0)
|
27(32.5)
|
1(2.3)
|
0.58(0.48–0.70)
|
0.0001
|
|
Severe sepsis
|
21(16.5)
|
17(20.5)
|
4(9.0)
|
0.76(0.59–0.99)
|
0.07
|
|
Shock
|
63(49.6)
|
25(30.1)
|
38(86.4)
|
2.28(1.66–3.12)
|
0.0001
|
|
Infection site (%)
|
|
Lungs
|
46(36.2)
|
23(27.7)
|
23(52.7)
|
1.48(1.07–2.03)
|
0.005
|
|
Urine
|
51(40.2)
|
39(47.0)
|
12(27.3)
|
0.75(0.59–0.96)
|
0.02
|
|
Blood
|
21(16.5)
|
11(13.2)
|
10(22.7)
|
1.29(0.84–1.99)
|
0.13
|
|
Tissue
|
11 (8.7)
|
7(8.4)
|
4(9.1)
|
1.02(0.64–1.64)
|
0.56
|
|
Others
|
8(8.0)
|
8(9.6)
|
0
|
0.63(0.54–0.72)
|
0.02
|
|
Pathogen (%)
|
|
K. pneumoniae
|
113(89.0)
|
74(89.2)
|
39(88.6)
|
0.98(0.64–1.48)
|
0.57
|
|
Polymyxin-resistant
|
27(21.3)
|
17(20.5)
|
10(22.7)
|
1.04(0.75–1.44)
|
0.46
|
|
Polymicrobial
|
55(43.3)
|
34(41.0)
|
21(47.7)
|
1.10(0.84–1.42)
|
0.29
|
|
Co-infection A. baumannii
|
36(28.3)
|
22(26.5)
|
14(31.8)
|
1.09(0.81–1.47)
|
0.33
|
|
Co-infection P. aeruginosa
|
13(10.2)
|
7(8.4)
|
6 (13.6)
|
1.23(0.73–2.08)
|
0.26
|
|
blaKPC+
|
96(75.6)
|
68(81.9)
|
28(63.6)
|
0.68(0.46–1.00)
|
0.02
|
- CRE carbapenem-resistant Enterobacteriaceae, RR relative risk, CI confidence interval, SD Standard deviation, LOS length of stay, IQR interquartile range, UTI urinary tract infection
