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Table 3 Comparison between the predisposed hosts and normal hosts (N = 34)

From: Characteristics and outcomes of cryptococcal meningitis in HIV seronegative children in Beijing, China, 2002–2013

 

Normal hosts (%) (n = 26)

Predisposed hosts (%) (n = 8)

P

Age (year)

5 (3–9)

7 (4–10)

0.900

Sex (Male: Female)

19:7

1:1

0.388

Area (rural)

21 (80.8)

5 (62.5)

0.355

Contacting history

10 (38.5)

5 (62.5)

0.417

Time to diagnosis (day)

30 (20–56)

25 (13–56)

0.759

Hospitalization (day)

41 ± 25

53 ± 44

0.352

Daily cost (RMB)

846 (567–1615)

1080 (621–1080)

0.138

Disseminated cryptococcosis

14 (53.8)

2 (25.0)

0.233

Manifestations

 Fever

39.2 ± 0.7

38.9 ± 0.8

0.242

 Headache

14 (53.8)

7 (87.5)

0.116

 Vomiting

14 (53.8)

7 (87.5)

0.116

 Altered mental status

5 (19.2)

5 (62.5)

0.031*

 Seizure

4 (15.4)

5 (62.5)

0.017*

 Vision damage

4 (15.4)

4 (50.0)

0.066

 Neck stiffness

13 (50.0)

5 (62.5)

0.693

Blood

 WBC (×109/L)

12.4 (8.6–16.3)

10.2 (8.8–11.3)

0.274

 CRP (mg/L)

11.9 (0–63.5)

16 (0–30.9)

0.592

 ESR (mm/h)

50 (26–79)

10 (1–52)

0.037*

 EO (×109/L)

0.72 (0.31–1.77)

0.38 (0.2–1.24)

0.504

CSF

 WBC (×106/L)

32 (10–113)

25 (7–102)

0.313

 Glu (mmol/L)

2.24 ± 1.23

2.80 ± 1.92

0.332

 Pro (mg/L)

625 (436–890)

660 (386–938)

0.528

Prognosis

 Success at discharge

16 (61.5)

6 (75.0)

0.618

 Success at follow-up

4/10 (40.0)

3/5 (60.0)

0.608

  1. *P < 0.05