Skip to main content

Table 3 Comparison between the predisposed hosts and normal hosts (N = 34)

From: Characteristics and outcomes of cryptococcal meningitis in HIV seronegative children in Beijing, China, 2002–2013

  Normal hosts (%) (n = 26) Predisposed hosts (%) (n = 8) P
Age (year) 5 (3–9) 7 (4–10) 0.900
Sex (Male: Female) 19:7 1:1 0.388
Area (rural) 21 (80.8) 5 (62.5) 0.355
Contacting history 10 (38.5) 5 (62.5) 0.417
Time to diagnosis (day) 30 (20–56) 25 (13–56) 0.759
Hospitalization (day) 41 ± 25 53 ± 44 0.352
Daily cost (RMB) 846 (567–1615) 1080 (621–1080) 0.138
Disseminated cryptococcosis 14 (53.8) 2 (25.0) 0.233
Manifestations
 Fever 39.2 ± 0.7 38.9 ± 0.8 0.242
 Headache 14 (53.8) 7 (87.5) 0.116
 Vomiting 14 (53.8) 7 (87.5) 0.116
 Altered mental status 5 (19.2) 5 (62.5) 0.031*
 Seizure 4 (15.4) 5 (62.5) 0.017*
 Vision damage 4 (15.4) 4 (50.0) 0.066
 Neck stiffness 13 (50.0) 5 (62.5) 0.693
Blood
 WBC (×109/L) 12.4 (8.6–16.3) 10.2 (8.8–11.3) 0.274
 CRP (mg/L) 11.9 (0–63.5) 16 (0–30.9) 0.592
 ESR (mm/h) 50 (26–79) 10 (1–52) 0.037*
 EO (×109/L) 0.72 (0.31–1.77) 0.38 (0.2–1.24) 0.504
CSF
 WBC (×106/L) 32 (10–113) 25 (7–102) 0.313
 Glu (mmol/L) 2.24 ± 1.23 2.80 ± 1.92 0.332
 Pro (mg/L) 625 (436–890) 660 (386–938) 0.528
Prognosis
 Success at discharge 16 (61.5) 6 (75.0) 0.618
 Success at follow-up 4/10 (40.0) 3/5 (60.0) 0.608
  1. *P < 0.05