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BMC Infectious Diseases

Open Access
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Epidemiology and outcome of Clostridium difficile infections in patients hospitalized in Internal Medicine: findings from the nationwide FADOI-PRACTICE study

  • Giorgio Cioni1,
  • Pierluigi Viale2,
  • Stefania Frasson3,
  • Francesco Cipollini4,
  • Francesco Menichetti5,
  • Nicola Petrosillo6,
  • Sergio Brunati7,
  • Patrizia Spigaglia8,
  • Chiara Vismara9,
  • Alessandra Bielli9,
  • Fabrizio Barbanti8,
  • Giancarlo Landini10,
  • Grazia Panigada11,
  • Gualberto Gussoni3Email author,
  • Erminio Bonizzoni12,
  • Giovanni Pietro Gesu9 and
  • for the Research Department of FADOI
BMC Infectious DiseasesBMC series – open, inclusive and trusted201616:656

Received: 26 June 2016

Accepted: 25 October 2016

Published: 8 November 2016

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting

Original Submission
26 Jun 2016 Submitted Original manuscript
Author responded Author comments
Reviewed Reviewer Report
Resubmission - Version 2
Submitted Manuscript version 2
Author responded Author comments
Resubmission - Version 3
Submitted Manuscript version 3
Author responded Author comments
Resubmission - Version 4
Submitted Manuscript version 4
25 Oct 2016 Editorially accepted
8 Nov 2016 Article published 10.1186/s12879-016-1961-9

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article and author comments to reviewers are available by contacting All previous versions of the manuscript and all author responses to the reviewers are also available.

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Authors’ Affiliations

Department of Internal Medicine, Pavullo nel Frignano Hospital
Infectious Diseases Unit, Teaching Hospital “Policlinico S. Orsola Malpighi”, Alma Mater Studiorum University of Bologna
Clinical Research Department, FADOI Foundation
Internal Medicine, Hospital “Vittorio Emanuele II”
Infectious Diseases Unit, University Hospital of Pisa
2nd Infectious Diseases Division, National Institute for Infectious Diseases, “Lazzaro Spallanzani” IRCCS
Department of Internal Medicine, Abbiategrasso Hospital
Department of Infectious, Parasitic and Immune-mediated Diseases, Istituto Superiore di Sanità
Clinical Chemistry and Microbiology Laboratory, Niguarda Ca’ Granda Hospital
Department of Internal Medicine, “Santa Maria Nuova” Hospital
Department of Internal Medicine, “S.S. Cosma e Damiano” Hospital
Section of Medical Statistics and Biometry “GA Maccacaro”, Department of Clinical Science and Community, University of Milan