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Table 3 Factors associated with delayed recovery from acute febrile illness among adult patients presenting at Singapore polyclinics between December 2007 and February 2013

From: Characteristics of acute febrile illness and determinants of illness recovery among adults presenting to Singapore primary care clinics

Variableb

Unadjusted TRa (95 % CI)

P value

Adjusted TRa (95 % CI)

P value

Type of employment

 Blue-collar workers

1

<0.0001

1

0.0035

 White-collar workers

1.10 (1.03–1.16)

 

1.08 (1.02–1.15)

 

 Other

1.29 (1.11–1.51)

 

1.16 (1.00–1.34)

 

 Unemployed

1.13 (1.07–1.20)

 

1.10 (1.03–1.17)

 

Number of symptoms at initial consultation (excluding fever)

1.04 (1.03–1.05)

<0.0001*

1.03 (1.02–1.03)

<0.0001*

Hospitalization as a result of AFI

 No

1

<0.0001

1

<0.0001

 Yes

1.96 (1.72–2.22)

 

1.59 (1.39–1.82)

 

WBC count at baseline (x103 cells/μL)

  < 4 (Low)

1.35 (1.25–1.46)

 

1.27 (1.18–1.37)

 

 4–11 (Normal)$

1

<0.0001

1

<0.0001

  > 11 (High)

0.92 (0.87–0.98)

 

0.94 (0.88–1.00)

 

Analgesic use

 No

1

<0.0001

1

<0.0001

 Yes

1.21 (1.15–1.27)

 

1.21 (1.15–1.28)

 

Cough medicine use

 No

1

<0.0001

1

<0.0001

 Yes

1.29 (1.22–1.36)

 

1.14 (1.08–1.20)

 

Antibiotic use

 No

1

<0.0001

1

<0.0001

 Yes

1.21 (1.13–1.29)

 

1.14 (1.07–1.21)

 
  1. TR Time (Illness duration) ratio, AFI Acute Febrile Illness, WBC White Blood Cells
  2. a A TR smaller than 1 means the factor is associated with longer illness duration, while a TR greater than 1 means the factors is associated with shorter illness duration compared to reference factor
  3. b Age, gender, and polyclinic variables are adjusted for in the model as confounding factors and are not shown
  4. * p value for linear trend