|
Variable
|
Total No. = 383
|
Plasma Viral load (>5, 000 copies/uL) No. = 28
|
Incidence rate per 1000 person-years
|
uHR (95 % CI)
|
P-value
|
aHR (95 % CI) Adjusted for all variables with P < 5 % at unadjusted level & WHO clinical stage
|
P-value
|
|---|
|
Age in years
|
|
Below 30
|
169 (44.1)
|
12
|
57.2 (32.5-100.7)
|
1
| | | |
|
Above 30
|
214 (55.9)
|
16
|
58.7 (35.9-95.7)
|
0.98 (0.46-2.08)
|
0.947
| | |
|
Residence
|
|
Rural
|
294 (76.8)
|
25
|
67.3 (45.5-99.7)
|
1
| | | |
|
Urban
|
89 (23.2)
|
3
|
26.9 (8.7-83.5)
|
0.40 (0.12-1.33)
|
0.134
| | |
|
Marital status
|
|
Single
|
54 (14.1)
|
6
|
103.2 (46.4-229.8)
|
1
| | | |
|
Married
|
234 (61.1)
|
15
|
50.6 (30.5-83.8)
|
0.36 (0.14-0.95)
|
0.05
| | |
|
Separated
|
71 (18.5)
|
6
|
62.8 (28.2-139.8)
|
0.43 (0.13-1.35)
|
0.148
| | |
|
One partner is dead
|
24 (6.3)
|
1
|
31.0 (4.4-219.8)
|
0.20 (0.02-1.67)
|
0.136
| | |
|
Occupation
|
|
Formal employment
|
79 (20.6)
|
7
|
72.1 (34.4-151.3)
|
1
| | | |
|
Self-employment
|
167 (43.6)
|
11
|
52.0 (28.8-93.9)
|
0.64 (0.25-1.67)
|
0.362
| | |
|
Not employed
|
137 (35.8)
|
10
|
57.4 (30.9-106.8)
|
0.73 (0.28-1.91)
|
0.519
| | |
|
Educational level
|
|
None
|
41 (10.7)
|
4
|
76.1 (28.6-202.8)
|
1
| | | |
|
Primary
|
95 (24.8)
|
4
|
32.3 (12.1-86.0)
|
0.40 (0.10-1.61)
|
0.199
| | |
|
Secondary
|
154 (40.2)
|
12
|
63.1 (35.9-111.2)
|
0.86 (0.28-2.67)
|
0.795
| | |
|
Tertiary
|
93 (24.3)
|
8
|
68.9 (34.5-137.8)
|
0.96 (0.29-3.19)
|
0.946
| | |
|
Religion
|
|
Catholic
|
203 (53.0)
|
14
|
53.9 (31.9-91.0)
|
1
| | | |
|
Moslem
|
46 (12.0)
|
2
|
38.4 (9.6-153.4)
|
0.78 (0.18-3.46)
|
0.749
| | |
|
Anglican
|
134 (35.0)
|
12
|
70.3 (39.9-123.7)
|
1.28 (0.59-2.77)
|
0.529
| | |
|
Tribe
|
|
Lugbara
|
290 (75.7)
|
17
|
47.3 (29.4-76.1)
|
1
|
1
| | |
|
Ma’ di
|
14 (3.7)
|
1
|
57.7 (8.1-409.8)
|
1.20 (0.16-9.04)
|
0.860
| | |
|
Luo
|
79 (20.6)
|
10
|
94.2 (50.7-175.2)
|
1.82 (0.83-3.94)
|
0.134
| | |
|
Sex
|
|
Male
|
145 (37.9)
|
14 (9.7)
|
82.0 (48.2-138.4)
|
1
| |
1
| |
|
Female
|
238 (62.1)
|
14 (5.9)
|
44.9 (26.6-75.8)
|
0.45 (0.21-0.95)
|
0.035
|
0.45 (0.19-1.03)
|
0.059
|
|
Baseline WHO staging
| | | |
1
| |
1
| |
|
I/II
|
359 (93.7)
|
21 (5.8)
|
59.6 (40.9-86.9)
|
0.60 (0.08-4.40)
|
0.612
|
0.60 (0.08-4.80)
|
0.632
|
|
III/IV
|
24 (6.3)
|
7 (29.2)
|
33.9 (4.8-240.4)
| | | | |
|
Baseline weight/Kgs
|
|
Less or equals 56 Kgs
|
194 (50.7)
|
20 (10.3)
|
82.0 (52.9-127.1)
|
1
| |
1
| |
|
More than 56 Kgs
|
189 (49.4)
|
8 (4.2)
|
33.5 (16.8-67.0)
|
0.39 (0.17-0.89)
|
0.025
|
1.14 (0.31-4.14)
|
0.845
|
|
1-kg increase
| | | |
0.92 (0.86-0.98)
|
0.008
|
0.86 (0.76-0.96)
|
0.008
|
|
Baseline CD4 cells/uL
|
|
Less or equals 250 cells/uL
|
192 (50.1)
|
21 (10.9)
|
92.3 (60.2-141.6)
|
1
| |
1
| |
|
More than 250 cells/uL
|
191 (49.9)
|
7 (3.7)
|
27.4 (13.1-57.6)
|
0.26 (0.11-0.61)
|
0.002
|
0.32 (0.08-1.20)
|
0.091
|
|
1-CD4 cell increase
| | | |
0.99 (0.99-0.10)
|
0.005
|
1.01 (1.00-1.01)
|
0.133
|
|
Recent CD4 cells/uL
|
|
Less or equals 362 cells/uL
|
194 (50.7)
|
21 (10.8)
|
84.9 (55.3-130.1)
|
1
| |
1
| |
|
More than 362 cells/uL
|
189 (49.3)
|
7 (3.7)
|
29.8 (14.2-62.4)
|
0.36 (0.15-0.85)
|
0.021
|
5.02 (1.11-22.72)
|
0.056
|
|
1-CD4 cell increase/uL
| | | |
0.99 (0.99-1.00)
|
<0.001
|
0.99 (0.98-0.99)
|
<0.001
|
|
HIV sero-status disclosure
|
|
No
|
68 (17.8)
|
14 (20.6)
|
177.9 (105.4-300.4)
|
1
| |
1
| |
|
Yes
|
315 (82.3)
|
14 (44.4)
|
34.7 (20.5-58.5)
|
0.18 (0.08-0.37)
|
<0.001
|
0.15 (0.06-0.33)
|
<0.001
|
-
Note
- -Percentages calculated as row percentages (n/N)
- -Level of significance was 5 %
- -Bolded P-values are significant at 5 %
- -uHR Unadjusted Hazard Ratio, aHR Adjusted Hazard Ratio, CI Confidence interval, WHO World Health Organization, CD4 Cluster of Cell Differentiation-4
