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Table 2 Diagnostic performance* of the Leucocyte Esterase Test (LET) after a reading time of 2 min (“LET 2 m”) and 5 min (“LET 5 m”) in the detection of urogenital Chlamydia Trachomatis (Ct) among male patients, Dermatological Service in Paramaribo, Suriname, 2008–2010

From: Leucocyte esterase dip-stick test as a point-of-care diagnostic for urogenital chlamydia in male patients: A multi-center evaluation in two STI outpatient clinics in Paramaribo and Amsterdam

  N LET + NAAT+ LET-NAAT+ LET + NAAT- LET- NAAT- Sens. (95 % CI) Spec. (95 % CI) PPV (95 % CI) NPV (95 % CI) Agr. Kappa
LET 2 m
 ALL 412 87 7 197 121 92.6 % (85.3–97.0) 38.1 % (32.7–43.6) 30.6 % (27.3–36.4) 94.5 % (89.1–97.8) 50.5 % 0.179
 Sympto-matic patients 279 71 6 141 61 92.2 % (83.8–97.1) 30.2 % (24.0–37.0) 33.5 % (27.2–40.3) 91.0 % (81.5–96.6) 47.3 % 0.145
 Asympto-matic patients 133 16 1 56 60 94.1 % (71.3–99.9) 51.7 % (42.3–61.1) 22.2 % (13.8–32.9) 98.4 % (91.2–100) 57.1 % 0.193
 <25 years 109 29 0 47 33 100 % (88.1–100) 41.3 % (30.4–52.8) 38.2 % (27.2–50.0) 100 % (89.4–100) 56.9 % 0.272
LET 5 m
 ALL 412 91 3 265 53 96.8 % (91.0–99.3) 16.7 % (12.7–21.2) 25.6 % (21.1–30.4) 94.6 % (85.1–98.9) 35.0 0.068
  1. *Sensitivity (Sens.), Specificity (Spec.), Positive Predictive Value (PPV), Negative Predictive Value (NPV), Agreement (Agr.) and Kappa