Fig. 5
From: A DNA vaccine targeting TcdA and TcdB induces protective immunity against Clostridium difficile
Survival in vaccinated hamsters following challenge with C. difficile BI/NAP1/027. Hamsters (n = 6) were immunized with the DNA vaccine. Two weeks following the third immunization, hamsters were treated with clindamycin p.o. (10 mg/kg) and the following day received an intra-gastric challenge of 108 CFU C. diff BI/NAP1/027. *, P ≤ 0.05; ***, P ≤ 0.001. Data from two replicate experiments are shown