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Table 1 Characteristics of studiesa

From: World-wide variation in incidence of Acinetobacter associated ventilator associated pneumonia: a meta-regression

 

Multinational

Europeb

Mediterraneanb

Asiab

Middle Eastb

Central & South Americab

USA/Canadab

Ungroupedb

Sources [ref]

Additional file 1: Table S1

[S1-S4]

Additional file 1: Table S2

[S5-S37]

Additional file 1: Table S3

[S38-S57]

Additional file 1: Table S4

[S58-S64]

Additional file 1: Table S4

[S65-S73]

Additional file 1: Table S5

[S74-S81]

Additional file 1: Table S5

[S82-S96]

Additional file 1: Table S6

[S97-S100]

Number of groups

13

35

20

7

11

9

18

4

MV for >48 h for <75 %c

0

1

1

1

0

1

2

0

Trauma ICUsd

1

2

6

0

4

0

6

0

Bronchoscopic samplinge

3

18

13

1

1

1

7

1

Intervention period

1

2

0

0

1

1

1

0

Study publication year (range)

1993-2012

1988-2016

1987-2012

2001-2016

2000-2013

1995-2013

1987-2014

1987-2015

Numbers of patients per study group; median (IQR)

2082;

1029-3413

385;

145-764

194;

101-318

952;

301-16426

260;

100-724

270;

233-427

340;

277-678

174;

65-331

Duration of MV (days);

median (IQR)

6; 5-7

11; 7.4-14

8; 6.5-10.2

7.5; 6-9

8.9; 7.1-10

9.6; 7.6-10

5.5; 4–10.5

9.2; 4–10.6

VAP incidence;

        

 • per 1000 ventilator days;

  o mean; f

  o 95 % CI

30 · 6;

20 · 4–40 · 7

24 · 3;

18 · 1–30 · 4

29.8 %

21 · 4–38 · 2

29 · 7;

15.9–43 · 5

34 · 0;

22.9–44 · 9

31 · 5;

19 · 3–43 · 6

26 · 7;

17 · 9–35 · 5

33 · 7;

15 · 4–51 · 9

Acinetobacter (all) VAP incidenceg

        

 • per 1000 ventilator days;

  o mean; h

  o 95 % CI

4 · 2;

2 · 8–6 · 2

1 · 3;

0.7–2 · 5

3 · 5;

2.0–6 · 1

5.5;

2 · 4–12 · 8

8.8;

6 · 2–12 · 7

3 · 3;

1 · 8–6 · 2

1 · 2;

0 · 8–2 · 1

3 · 1;

1 · 9–5 · 2

Acinetobacter baumanii VAP incidence i

        

 • per 1000 ventilator days;

  o mean; j

  o 95 % CI

8 · 2;

0 · 7–3 · 5

0 · 51;

0.1–0 · 9

2 · 8;

1 · 4–5 · 4

6.6;

2 · 1–20 · 1

18.0;

9 · 8–33 · 1

4 · 4;

2 · 0–10 · 0

1 · 2;

0 · 6–2 · 6

 
  1. aAbbreviations; ICU, Intensive care unit; MV; Mechanical ventilation; NA not applicable; VAP ventilator associated pneumonia; IQR, interquartile range
  2. bEurope includes France, Germany, United Kingdom, Switzerland, Sweden, Iceland, and Poland; Mediterranean includes Spain, Italy, Greece and Tunisia; Asia includes China, India, Pakistan and Bangladesh; Middle East includes Turkey, Iraq, Lebanon and Saudi Arabia; Central & South America includes Argentina, Brazil, Chile, Colombia, Cuba and Guatemala; Northern America includes USA and Canada; Ungrouped includes Australia and South Africa
  3. cStudies for which less than 75 % of patients were reported to receive more than 48 h of mechanical ventilation
  4. dTrauma ICU defined as an ICU with >50 % of patient admissions for trauma
  5. eBronchoscopic versus tracheal sampling toward the diagnosis of VAP
  6. fMean VAP incidence (per 1000 MV days) was not significantly different between the six geographic regions; p = 0.74
  7. gAcinetobacter (all) refers to Acinetobacter regardless of whether listing in the original study was as Acinetobacter species, Acinetobacter baumanii, or other speciation
  8. hMean Acinetobacter VAP incidence (per 1000 MV days) was significantly different between the six geographic regions; p = 0.003
  9. iOnly from those studies that specified Acinetobacter baumanii
  10. jMean Acinetobacter VAP incidence from studies reporting as Acinetobacter baumanii (per 1000 MV days) was significantly different between the six geographic regions; p = 0.014
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BMC Infectious Diseases

ISSN: 1471-2334

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