Table 3 Susceptibility (of bacteria from blood cultures taken from neonates between 2 to 28 days) to antimicrobials used for empiric treatment of neonatal septicaemia

Gram negatives

220

200 (90.9)

72 (36.0)^a

188 (85.4)

92 (48.9)^a

173 (0.78)

102 (46.3)^b

C > B = A; p = 0.001

   Enterobacteriacea

160

145 (90.6)

44 (30.3)

149 (93.1)

75 (50.3)

131 (81.8)

78 (59.5)

   Acinetobacter species

43

40 (93.0)

22 (55.0)

39 (90.7)

17 (43.6)

31 (72.1)

17 (54.8)

   Pseudomonas species

16

15 (93.7)

6 (40.0)

-

-

11 (68.7)

7 (63.6)

  Others

1

Gram positives

811

762 (93.9)

276 (36.3)^b

770 (94.9)

144 (18.7)^a

723 (89.1)

468 (64.7)^c

C > B < A; p = 0.001

   Enterococcus species

36

29 (80.5)

8 (27.5)

34 (94.4)

9 (26.4)

-

-

   Staphylococcus aureus

159

143 (89.9)

64 (44.7)

151 (94.9)

22 (14.6)

142 (89.3)

82 (57.7)

  CoNS

549

539 (98.2)

183 (34.0)^b

540 (98.3)

97 (17.9)^a

531 (96.7)

366 (68.9)^c

C > B < A; p = 0.001

   Streptococcus species

58

51 (97.9)

21 (41.0)

45 (77.5)

16 (35.5)

50 (86.2)

20 (40.0)

  Others

9

Total

1031

962 (93.3)

_a348 (36.2)^b

958 (92.9)

_a236 (24.6)^a

896 (86.9)

_a570 (63.6)^c

C > B < A; p = 0.001

Total excluding CoNS

482

423 (87.8)

_a165 (39.0)^b

418 (86.7)

_b139 (33.2)^a

365 (75.7)

_b204 (55.8)^c

C > B < A; p = 0.001

Polymicrobial infections

25

16 (64.0)

3 (18.7)

14 (56.0)

3 (21.4)

16 (64.0)

6 (37.7)

C = B = A; p = 0.431

  2 organisms

22

14 (63.6)

2 (14.2)

12 (54.5)

2 (16.7)

15 (68.2)

5 (33.3)

  3 organisms

3

2 (66.7)

1 (50.0)

2 (66.7)

1 (50.0)

1 (33.3)

1 (100.0)