Table 2 Susceptibility (of bacteria from blood cultures taken from neonates less than 48 h old) to antimicrobials used for empiric treatment of neonatal BSI

Gram negatives

109

101 (92.6)

38 (37.6)^a

68 (62.4)

32 (47.1)^a

75 (68.8)

52 (69.3)^b

C > B = A; p = 0.001

  Enterobacteriacea

79

74 (93.7)

24 (32.4)

55 (69.6)

27 (49.1)

53 (67.1)

37 (69.8)

  Acinetobacter species

16

16 (100)

10 (62.5)

13 (81.2)

5 (38.4)

13 (81.2)

8 (61.5)

  Pseudomonas species

11

11 (100)

4 (36.4)

-

-

9 (81.8)

7 (77.7)

 Others

3

Gram positives

610

511 (83.8)

159 (31.1)^b

356 (58.4)

56 (15.7)^a

211 (34.6)

153 (72.5)^b

C > A > B; p = 0.001

  Enterococcus species

43

37 (86.1)

8 (21.6)

37 (86.1)

7 (18.9)

-

-

  Staphylococcus aureus

76

67 (88.2)

34 (50.7)

59 (77.6)

5 (8.5)

69 (90.7)

46 (66.7)

 CoNS

431

376 (87.2)

107 (28.5)

226 (52.4)

26 (11.5)

111 (25.7)

93 (83.7)

C > A > B; p = 0.001

  Streptococcus species

59

31 (52.5)

10 (32.3)

34 (57.6)

18 (30.5)

31 (52.5)

14 (45.2)

 Others

1

Total

719

612 (85.1)

_a197 (32.2)^b

424 (58.9)

_a 88 (20.7) ^a

286 (40.0)

_a205 (71.7)^c

C > A > B; p = 0.001

Total excluding CoNS

288

236 (81.9)

_a90 (38.1)^a

198 (68.8)

_b 62 (31.3)^a

175 (60.7)

_a112 (64.0)^b

C > B = A; p = 0.001

Polymicrobial infections

20

19 (95.0)

4 (21)^a

18 (90.0)

2 (11.1)^a

20 (100.0)

5 (25.0)^a

C = B = A; p = 0.540

 2 organisms

17

16 (94.1)

1 (6.3)

15 (88.2)

1 (6.7)

17 (100)

4 (23.5)

 3 organisms

3

3 (100)

3 (100)

3 (100)

1 (33.3)

3 (100)

1 (33.3)