|
Organisms
|
Susceptibility
|
|---|
| |
Ampicillin + Gentamicin (A)
|
Ampicillin + Cefotaxime (B)
|
Cloxacillin + Gentamicin (C)
|
Regimen coverage
|
|---|
| |
Number of isolates
|
Number Tested (%)
|
Number susceptible (%)
|
Number Tested (%)
|
Number susceptible (%)
|
Number Tested (%)
|
Number susceptible (%)
|
|---|
|
Gram negatives
|
109
|
101 (92.6)
|
38 (37.6)a
|
68 (62.4)
|
32 (47.1)a
|
75 (68.8)
|
52 (69.3)b
|
C > B = A; p = 0.001
|
|
Enterobacteriacea
|
79
|
74 (93.7)
|
24 (32.4)
|
55 (69.6)
|
27 (49.1)
|
53 (67.1)
|
37 (69.8)
| |
|
Acinetobacter species
|
16
|
16 (100)
|
10 (62.5)
|
13 (81.2)
|
5 (38.4)
|
13 (81.2)
|
8 (61.5)
| |
|
Pseudomonas species
|
11
|
11 (100)
|
4 (36.4)
|
-
|
-
|
9 (81.8)
|
7 (77.7)
| |
|
Others
|
3
| | | | | | | |
|
Gram positives
|
610
|
511 (83.8)
|
159 (31.1)b
|
356 (58.4)
|
56 (15.7)a
|
211 (34.6)
|
153 (72.5)b
|
C > A > B; p = 0.001
|
|
Enterococcus species
|
43
|
37 (86.1)
|
8 (21.6)
|
37 (86.1)
|
7 (18.9)
|
-
|
-
| |
|
Staphylococcus aureus
|
76
|
67 (88.2)
|
34 (50.7)
|
59 (77.6)
|
5 (8.5)
|
69 (90.7)
|
46 (66.7)
| |
|
CoNS
|
431
|
376 (87.2)
|
107 (28.5)
|
226 (52.4)
|
26 (11.5)
|
111 (25.7)
|
93 (83.7)
|
C > A > B; p = 0.001
|
|
Streptococcus species
|
59
|
31 (52.5)
|
10 (32.3)
|
34 (57.6)
|
18 (30.5)
|
31 (52.5)
|
14 (45.2)
| |
|
Others
|
1
| | | | | | | |
|
Total
|
719
|
612 (85.1)
|
a197 (32.2)b
|
424 (58.9)
|
a 88 (20.7) a
|
286 (40.0)
|
a205 (71.7)c
|
C > A > B; p = 0.001
|
|
Total excluding CoNS
|
288
|
236 (81.9)
|
a90 (38.1)a
|
198 (68.8)
|
b 62 (31.3)a
|
175 (60.7)
|
a112 (64.0)b
|
C > B = A; p = 0.001
|
|
Polymicrobial infections
|
20
|
19 (95.0)
|
4 (21)a
|
18 (90.0)
|
2 (11.1)a
|
20 (100.0)
|
5 (25.0)a
|
C = B = A; p = 0.540
|
|
2 organisms
|
17
|
16 (94.1)
|
1 (6.3)
|
15 (88.2)
|
1 (6.7)
|
17 (100)
|
4 (23.5)
| |
|
3 organisms
|
3
|
3 (100)
|
3 (100)
|
3 (100)
|
1 (33.3)
|
3 (100)
|
1 (33.3)
| |
- Based on in-vitro susceptibility. Data on isolates with insufficient numbers (n ≤ 5) not shown. For polymicrobial infections, all isolates were susceptible to at least one of the treatment antibiotics
- A, Ampicillin plus Gentamicin; B, Ampicillin plus cefotaxime; C, Cloxacillin plus gentamicin; CoNS, Coagulase negative Staphylococcus species. Other Gram-negatives included Neisseria species (n = 1), Stenophromonas species (n = 1) and Moraxella species (n = 1). Other Gram-positives included Micrococcus species
- Differing superscripts across row denotes differences in the proportion of susceptible isolates to antimicrobial regimen. Differences in proportions computed by Chi square with Marascuilo’s Post Hoc Multiple proportion comparisons at p-value <0.05. Differing subscripts within a column denotes differences in the proportion of susceptible isolates to antimicrobial regimen
