Skip to main content

Table 2 Mutations in the rpoB, katG, pncA and embB genes with the associated MICs and genotypes of the drug susceptible isolates

From: Mechanisms of first-line antimicrobial resistance in multi-drug and extensively drug resistant strains of Mycobacterium tuberculosis in KwaZulu-Natal, South Africa

Isolate Genotype MIC (mg/L) Mutation Profile
RIF INH EMB rpoB katG pncA embB
TF1538 Unique 1 ≤0.125 2 - - - -
TF1413 Beijing 1 16 2 - G1388T - -
TF1582 Beijing 1 ≤0.125 2 - G1388T - -
TF832 F11V 1 ≤0.125 2 - - - -
TF1519 Beijing 1 ≤0.125 2 - - - -
TF1001 Unique 1 ≤0.125 2 - - - -
TF933 Unique 1 ≤0.125 2 - - - -
P090811 Beijing 1 ≤0.125 2 - G1388T - -
P090802 Beijing 1 ≤0.125 2 - G1388T - -
P090804 Beijing 1 ≤0.125 2 - G1388T - -