| |
CNPS (N = 71)
|
TS (N = 94)
|
P-value
|
|---|
|
Duration of symptoms
|
|
<1 month
|
32 (45.1 %)
|
25 (26.6 %)
|
0.002
|
|
1–3 months
|
32 (45.1 %)
|
44 (46.8 %)
|
|
> 4 months
|
7 (9.9 %)
|
25 (26.6 %)
|
|
Neurologic stage
|
|
No pain
|
0
|
3 (3.2 %)
|
0.164
|
|
Spine pain
|
28 (39.4 %)
|
52 (55.3 %)
|
|
Radiating pain
|
38 (53.5 %)
|
26 (26.6 %)
|
|
Weakness
|
5 (7.0 %)
|
13 (13.8 %)
|
|
Sepsis
|
7 (9.9 %)
|
15 (16.0 %)
|
0.254
|
|
Initial body temperature over 38 °C
|
11 (15.5 %)
|
27 (31.8 %)
|
0.018
|
|
WBC (/mm3) (median with IQR)
|
8600 (7070–11,100)
|
7890 (6098–10,293)
|
0.030
|
|
CRP a (mg/dL) (median with IQR)
|
4.3 (2.4–8.1)
|
2.8 (1.0–7.2)
|
0.018
|
|
IGRA b
|
|
Positive
|
8 (27.6 %)
|
38 (79.2 %)
|
<0.001
|
|
Negative
|
19 (65.5 %)
|
9 (18.8 %)
|
|
Psoas abscess
|
11 (15.5 %)
|
31 (33.0 %)
|
0.011
|
|
Paravertebral abscess
|
35 (49.3 %)
|
70 (74.5 %)
|
0.001
|
|
Epidural abscess
|
39 (54.9 %)
|
50 (53.2 %)
|
0.824
|
|
Involved vertebrae
|
|
Cervical
|
2 (2.8 %)
|
3 (3.2 %)
|
N.A.
|
|
Cervicothoracic
|
0
|
6 (6.4 %)
|
|
Thoracic
|
5 (7.0 %)
|
25 (26.6 %)
|
|
Thoracolumbar
|
3 (4.2 %)
|
9 (9.6 %)
|
|
Lumbar
|
47 (66.2 %)
|
43 (45.7 %)
|
|
Lumbosacral
|
14 (19.7 %)
|
6 (6.4 %)
|
|
Sacral
|
0
|
1 (1.1 %)
|
|
Cervical and Lumbar (skipped lesion)
|
0
|
1 (1.1 %)
|
|
Number of vertebrae involved
|
|
1–2
|
58 (81.7 %)
|
65 (69.1 %)
|
0.067
|
|
3–5
|
13 (18.3 %)
|
29 (30.9 %)
|
- Abbreviations: WBC white blood cell count, IQR interquartile range, CRP C-reactive protein, IGRA Interferon gamma release assay, TS tuberculous spondylitis, CNPS culture negative pyogenic spondylitis, N.A not applicable
- aC-Reactive Protein value was missing in 1 case of tuberculous spondylitis
- bThe IGRA was performed in 76 patients: 48 with TS and 29 with CNPS. IGRA result was indeterminate in one case of tuberculous spondylitis and two cases of culture negative pyogenic spondylitis
