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Table 5 Clinical performance of sTREM-1 combined with either SAPS II or SOFA score values in predicting all cause ICU mortality

From: Significance of soluble triggering receptor expressed on myeloid cells-1 elevation in patients admitted to the intensive care unit with sepsis

  AUROCC [95 % CI] Se (%) [95 % CI] Sp (%) [95 % CI] PPV (%) [95 % CI] NPV (%) [95 % CI] Positive LR [95 % CI] Negative LR [95 % CI]
sTREM-1 (>954.4 ng/L) & SAPS II (>67.5) 0.68 [0.59–0.78] 38.8 % [25.2–53.8] 98.6 % [95.0–99.8] 91.3 % [58.8–100] 80.3 % [79.3–83.3] 27.30 [5.08–261.50] 0.63 [0.48–0.78]
sTREM-1 (>954.4 ng/L) & SOFA D1 (>7.5) 0.70 [0.61–0.80] 55.1 % [40.2–69.3] 85.8 % [78.9–91.1] 57.4 % [41.9–72.2] 84.6 % [77.8–89.8] 3.88 [3.20–29.70] 0.57 [0.41–0.76]
  1. AUROCC area under receiver operating characteristics curve, Se sensitivity, Sp specificity, PPV positive predictive value, NPV negative predictive value, LR likelihood ratio, sTREM-1 soluble triggering receptor expressed on myeloid cells-1, SAPS simplified acute physiologic score, SOFA sequential organ failure assessment, ICU intensive care unit