| |
AUROCC [95 % CI]
|
Se (%) [95 % CI]
|
Sp (%) [95 % CI]
|
PPV (%) [95 % CI]
|
NPV (%) [95 % CI]
|
Positive LR [95 % CI]
|
Negative LR [95 % CI]
|
|---|
|
sTREM-1 (>954.4 ng/L)
|
0.64 [0.54–0.74]
|
54.5 % [40.5–68.0]
|
78.0 % [70.3–84.5]
|
49.2 % [40.5–54.6]
|
81.5 % [70.3–92.4]
|
2.48 [1.36–4.39]
|
0.58 [0.37–0.85]
|
|
PCT (>11.1 ug/L)
|
0.62 [0.53–0.71]
|
66.7 % [52.5–78.9]
|
55.8 % [47.1–64.2]
|
37.1 % [28.3–42.5]
|
81.0 % [67.1–91.4]
|
1.51 [0.99–2.20]
|
0.60 [0.33–1.01]
|
|
Lactate (>3.2 mmol/L)
|
0.71 [0.62–0.80]
|
61.2 % [46.2–74.8]
|
78.3 % [70.4–84.8]
|
50.0 % [37.7–61.1]
|
84.8 % [70.4–92.0]
|
2.82 [1.56–4.92]
|
0.49 [0.30–0.76]
|
|
SAPS II (>67.5)
|
0.86 [0.80–0.91]
|
63.8 % [48.5–77.3]
|
91.3 % [85.3–95.4]
|
71.4 % [56.6–90.2]
|
88.1 % [81.3–90.9]
|
7.34 [3.30–16.80]
|
0.40 [0.24–0.60]
|
|
SOFA D1 (>7.5)
|
0.78 [0.71–0.85]
|
87.5 % [74.7–95.2]
|
55.1 % [46.4–63.7]
|
40.8 % [35.5–45.3]
|
92.6 % [74.7–100]
|
1.95 [1.39–2.62]
|
0.23 [0.07–0.54]
|
- AUROCC area under receiver operating characteristics curve, Se sensitivity, Sp specificity, PPV positive predictive value, NPV negative predictive value, LR likelihood ratio, PCT procalcitonin, sTREM-1 soluble triggering receptor expressed on myeloid cells-1, SAPS simplified acute physiologic score, SOFA sequential organ failure assessment, ICU intensive care unit
