Recombinant domains III of Tick-Borne Encephalitis Virus envelope protein in combination with dextran and CpGs induce immune response and partial protectiveness against TBE virus infection in mice

Table 1 Representation of amino acid residues in three positions of different TBEV subtypes E protein

Amino acid residue and its position in the E protein			Number of strains of different TBEV subtypes^a				Total
313	317	331	E	FE	S	ND
A	T	T			67	19	86
T	T	T	1		28	7	36
T	V	T	3			2	5
A	I	T			2	2	4
T	I	T			2		2
T	I	A		54	1	56^b	111
T	A	A				1	1
T	T	A		4		5^c	9
T	A	S	2			6	8
T	A	T	55			80	135
Total number of strains			61	58	100	179	397

^a)E is European subtype, FE is Far-Eastern subtype, S is Siberian subtype, ND is “not determined”, e.g. the subtype is not specified in amino acid sequence annotation and in the corresponding article. The most common variants are shown in bold, genotypes are listed according to the sequence authors
^b)Strain 886-84, which was annotated as genotype 5 in [25], belongs to this group
^c)Strain 178-79, which was annotated as genotype 4 in [25], belongs to this grou

ISSN: 1471-2334