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Fig. 3 | BMC Infectious Diseases

Fig. 3

From: Recombinant domains III of Tick-Borne Encephalitis Virus envelope protein in combination with dextran and CpGs induce immune response and partial protectiveness against TBE virus infection in mice

Fig. 3

Survival (a) and morbidity (b) curves. Tick-E-Vac means group of mice (n = 10) immunized with Tick-E-Vac by standard scheme; 3DIII + AD means group of mice (n = 10) immunized with 3DIII + AD by standard scheme, Prime-boost means group of mice (n = 10) immunized with Tick-E-Vac and 3DIII + AD by prime-boost scheme. Group of mice (n = 10) immunized by saline was used as a control. Mice were assumed as ill if showing clinical symptoms (generalized intoxication, paresis, paralysis) or if losing weight 1.5 g or more per 3 days or longer. Statistical significance was determined by Log-rank test. * p < 0.01 compared with a control (saline), # p < 0.01 compared with Tick-E-Vac

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BMC Infectious Diseases

ISSN: 1471-2334

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